5-(dimethylamino)-N-[2-(pyridin-2-ylmethylamino)ethyl]naphthalene-1-sulfonamide | 918866-39-4

• 英文名称: 5-(dimethylamino)-N-[2-(pyridin-2-ylmethylamino)ethyl]naphthalene-1-sulfonamide
• CAS: 918866-39-4
• 化学式: C₂₀H₂₄N₄O₂S
• 分子量: 384.502
• InChiKey: NPTDLQMCRXDCKA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  27
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  82.7
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  copper(II) nitrate trihydrate 、 5-(dimethylamino)-N-[2-(pyridin-2-ylmethylamino)ethyl]naphthalene-1-sulfonamide 在 3-[N-morpholino]propanesulfonic acid 作用下， 以 甲醇 、 水 为溶剂， 生成
  参考文献：
  名称：

  A selective fluorescent sensor for Cu2+ and its immobilization on CPG beads

  摘要：

  A new dansyl derived fluorescent sensor for Cu(II) ions (1) has been isolated by four-step organic synthesis with a good yield and characterized by NMR- and ESI-NIS methods. UV-Vis and fluorescent titrations of 1 with Cu(II), Co(II), Zn(II), Ni(II), Ca(II) and Mg(II) salts were performed. 1 forms a 1: 1 stable complex in solution (1 x 10(-6) M) with Cu(II) and does not form such complex with other metals. I has been attached to a CPG 1000/100 resin. The fluorescence images of CPG 1000/100 resin with I have shown strong fluorescence and complete absence of it in the presence of Cu(II) anions. (C) 2006 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.inoche.2006.03.004