| 952065-92-8

• CAS: 952065-92-8
• 化学式: C₃₂H₄₄N₂O₂Ru₂
• 分子量: 690.854
• InChiKey: SIUNLNMJDQGAHL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  以 四氢呋喃 为溶剂， 反应 24.0h， 以42%的产率得到
  参考文献：
  名称：

  钌和钴三核配合物催化4-取代吡啶的脱氢偶联

  摘要：

  The dehydrogenative coupling of 4-substituted pyridines catalyzed by a heterometallic trinuclear complex composed of Ru and Co, (Cp*Ru)(2)(Cp*Co)(mu-H)(3)(mu(3)-H) (1, Cp* = eta(5)-C5Me5), was investigated. When the pyridine substrate contains an electron donating group at the 4-position, complex 1 showed a high catalytic activity compared to di- and triruthenium complexes (Cp*Ru)(2)(mu-H)(4) (4) and (Cp*Ru)(3)(mu-H)(3)(mu(3)-H)(2) (5). The catalytic activity of 1 was also remarkably higher than the congeners of other group 9 metals, Ru2Rh (2) and Ru2Ir analogues (3). The distinctive reactivity of 1 was attributed to a paramagnetic intermediate, (Cp*Ru)(2){(dmbpy)Co}(mu-H)(mu(3)-H)(2) (12, dmbpy = 4,4'-dimethyl-2,2'-bipyridine), which was formed by the reaction of 1 with 4-picoline accompanied by the dissociation of the Cp* at the Co atom. The reaction of 12 with unsubstituted pyridine resulted in the elimination of 4,4'-dimethyl-2,2'-bipyridine, indicating that the Co atom in 12 acts as a dissociation site. In contrast to the reaction of 1 with 4-picoline, the reaction of 2 and 3 with 4-picoline afforded the corresponding mu 3-pyridyl complexes (Cp*Ru)(2)(Cp*M)(mu-H)(3)(mu(3)-eta(2)(11)-C5H3NCH3) (15, M = Rh; 16, M = Ir). 4-(Trifluoromethyl)pyridine was not dimerized by 1; however, a similar mu(3)-pyridyl complex, (Cp*Ru)(2)(Cp*Co)(mu-H)(3)(mu(3)-eta(2)(parallel to)-C5H3NCF3) (13), was obtained. The stability of the mu(3)-pyridyl complex is probably one of the reasons for the low catalytic activity of 2 and 3 in the coupling reaction.

  DOI：

  10.1021/acs.organomet.6b00277
• 作为产物：
  描述：

  4-甲氧基吡啶 、 tetra-μ-hydrido-bis[(pentamethyl-η5-cyclopentadienyl)ruthenium] 以 not given 为溶剂， 以99%的产率得到
  参考文献：
  名称：

  Dehydrogenative Coupling of 4-Substituted Pyridines Catalyzed by Diruthenium Complexes

  摘要：

  Coupling reaction of 4-substituted pyriclines via direct C-H bond activation was achieved by the use of diruthenium complexes 1 and 2. These reactions provide a variety of functionalized bipyridines in a selective manner without the formation of terpyridines.

  DOI：

  10.1021/ja074224u