[Cu(4-hydroxy-5-[N-(2-hydroxyphenyl)ethanimidoyl]-2H-1,3-thiazine-2,6(3H)-dione(-1H))(H2O)2Cl] | 1384865-64-8

• 英文名称: [Cu(4-hydroxy-5-[N-(2-hydroxyphenyl)ethanimidoyl]-2H-1,3-thiazine-2,6(3H)-dione(-1H))(H2O)2Cl]
• CAS: 1384865-64-8
• 化学式: C₁₂H₁₂ClCuN₂O₆S*H
• 分子量: 412.31
• InChiKey: NMAHQIRODQXJTC-ZERAJDFGSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  [Cu(4-hydroxy-5-[N-(2-hydroxyphenyl)ethanimidoyl]-2H-1,3-thiazine-2,6(3H)-dione(-1H))(H2O)2Cl] 以 neat (no solvent, solid phase) 为溶剂， 生成 copper(II) oxide
  参考文献：
  名称：

  Characterization, molecular modeling and antimicrobial activity of metal complexes of tridentate Schiff base derived from 5-acetyl-4-hydroxy-2H-1,3-thiazine-2,6(3H)-dione and 2-aminophenol

  摘要：

  Metal complexes of Ni(II), Co(II), Cd(II), VO(IV) and UO2(VI) as well as several Cu(II) salts, including Cl-, NO3- AcO-; and ClO4- with a tridentate O2N donor Schiff base ligand (H2L), synthesized by condensation of 5-acetyl-4-hydroxy-2H-1,3-thiazine-2,6(3H)-dione with 2-aminophenol, were prepared and characterized on the basis of elemental analyses, spectral, magnetic, molar conductance and thermal gravimetric analysis. Square planar, tetrahedral and octahedral geometries have been assigned to the prepared complexes. Molecular parameters of the ligand and its metal complexes have been calculated and correlated with the experimental data, and the changes of bond lengths are linearly correlated with IR data. The antimicrobial activities of the synthesized compounds were tested in vitro against the sensitive organisms Staphylococcus aureus as Gram positive bacteria, Proteus vulgaris as Gram negative bacteria and Candida albicans as fungus strain, and the results are discussed. (C) 2012 Elsevier BM. All rights reserved.

  DOI：

  10.1016/j.saa.2012.04.030
• 作为产物：
  描述：

  4-hydroxy-5-[N-(2-hydroxyphenyl)ethanimidoyl]-2H-1,3-thiazine-2,6(3H)-dione 、 copper dichloride 在 LiOH*H₂O 作用下， 以 甲醇 为溶剂， 以80%的产率得到[Cu(4-hydroxy-5-[N-(2-hydroxyphenyl)ethanimidoyl]-2H-1,3-thiazine-2,6(3H)-dione(-1H))(H2O)2Cl]
  参考文献：
  名称：

  Characterization, molecular modeling and antimicrobial activity of metal complexes of tridentate Schiff base derived from 5-acetyl-4-hydroxy-2H-1,3-thiazine-2,6(3H)-dione and 2-aminophenol

  摘要：

  Metal complexes of Ni(II), Co(II), Cd(II), VO(IV) and UO2(VI) as well as several Cu(II) salts, including Cl-, NO3- AcO-; and ClO4- with a tridentate O2N donor Schiff base ligand (H2L), synthesized by condensation of 5-acetyl-4-hydroxy-2H-1,3-thiazine-2,6(3H)-dione with 2-aminophenol, were prepared and characterized on the basis of elemental analyses, spectral, magnetic, molar conductance and thermal gravimetric analysis. Square planar, tetrahedral and octahedral geometries have been assigned to the prepared complexes. Molecular parameters of the ligand and its metal complexes have been calculated and correlated with the experimental data, and the changes of bond lengths are linearly correlated with IR data. The antimicrobial activities of the synthesized compounds were tested in vitro against the sensitive organisms Staphylococcus aureus as Gram positive bacteria, Proteus vulgaris as Gram negative bacteria and Candida albicans as fungus strain, and the results are discussed. (C) 2012 Elsevier BM. All rights reserved.

  DOI：

  10.1016/j.saa.2012.04.030