(η5:η1-2-Me-4-Ph-C5H2CO2CH2CH2PPh2)Ru(trimethylphosphine)(phenylacetylene(-1H)) | 854375-86-3

• 英文名称: (η5:η1-2-Me-4-Ph-C5H2CO2CH2CH2PPh2)Ru(trimethylphosphine)(phenylacetylene(-1H))
• CAS: 854375-86-3
• 化学式: C₃₈H₃₈O₂P₂Ru
• 分子量: 689.736
• InChiKey: UDUXOQMVAFJDBH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  [(η5:η1-2-Me-4-Ph-C5H2CO2CH2CH2PPh2)Ru(trimethylphosphine)(acetonitrile)][PF6] 、 苯乙炔 在 Al₂O₃ 作用下， 以 二氯甲烷 为溶剂， 以82%的产率得到(η5:η1-2-Me-4-Ph-C5H2CO2CH2CH2PPh2)Ru(trimethylphosphine)(phenylacetylene(-1H))
  参考文献：
  名称：

  Diastereoselective Formation of Ruthenium-Isocyanide and -Acetylide Complexes with Planar-Chiral Cyclopentadienyl-Phosphine Ligands

  摘要：

  The reaction of ruthenium complexes [(eta(5):eta(1)-2-Me-4-R-C5H2CO2CH2CH2PPh2)Ru(PR'(3))(NCMe)] [PF6] (R = Me, Ph, Bu-t; R'= Ph, Me, OPh) possessing planar-chiral cyclopentadienyl-phosphine ligands with tert-butyl isocyanide resulted in the diastereoselective formation of ruthenium-isocyanide complexes (up to > 99% de) under kinetic control. The reaction with phenylacetylene followed by treatment with alumina gave acetylide complexes diastereoselectively (up to > 99% de). The configuration of the products was determined by X-ray analyses as well as NOE measurements. In both reactions, the stereochemistry of the ruthenium atom in the substrate did not influence the diastereoselectivity of the products, although the substituent on the cyclopentadienyl ring and the phosphorus ligands on the ruthenium atom showed steric effects on the selectivity.

  DOI：

  10.1021/om0500523