| 238743-63-0

• CAS: 238743-63-0
• 化学式: C₂₄H₃₆O₁₈P₂Ru
• 分子量: 775.557
• InChiKey: MXUYKDLXVMQJDW-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  [Ru2(μ2-CH3COO)2(CO)4 、 三(乙酰氧基甲基)膦 、 溶剂黄146 以 溶剂黄146 为溶剂， 生成
  参考文献：
  名称：

  The role of functionalized phosphines in the hydrogenation of carboxylic acids in the presence of phosphine substituted hydrido ruthenium complexes

  摘要：

  Hydride ruthenium carbonyl complexes substituted by functionalized phosphines such as H4Ru4(CO)(8)[P(CH2OCOR)(3)](4) have been synthesized and tested as catalysts in the hydrogenation of carboxylic acids. These complexes are more active than those reported previously, containing trialkyl- or triarylphosphines. On the basis of their behavior, their different activity has been explained in terms of an involvement of the phosphine ligand in the catalytic cycle. The ester group present in the phosphine P(CH2OCOR)(3) is hydrogenated to produce an alcohol (RCH2OH) and a P(CH2OH) group which, in turn, reacts with the free acid present in solution to restore the P(CH2OCOR) group. This hypothesis has been confirmed by the reactivity of the possible intermediate H4Ru4(CO)(8)[P(CH2OH)(3)](4) with acetic acid. Another support to this statement is the almost equal catalytic activity, displayed by H4Ru4(CO)(8)[P(CH2OCOR)(3)](4) complexes, whatever the R group present, in the phosphine ligand, in the hydrogenation of carboxylic acids. These complexes, on the other hand, are less active than the corresponding tributylphosphine substituted ones in the hydrogenation of alkenes and ketones. Finally when the phosphine ligand is P(CH2CH2COOCH3)(3) the ester group is not reduced and consequently the catalytic activity of this complex in the hydrogenation of carboxylic acids is very low. (C) 1999 Elsevier Science S.A. All rights reserved.

  DOI：

  10.1016/s0022-328x(99)00038-8