[Pd(py(SCH2C(O)Ph)-2)2Cl2] | 235084-26-1

• 英文名称: [Pd(py(SCH2C(O)Ph)-2)2Cl2]
• CAS: 235084-26-1
• 化学式: C₂₆H₂₂Cl₂N₂O₂PdS₂
• 分子量: 635.931
• InChiKey: IEMGPNAXIROFGN-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  [Pd(py(SCH2C(O)Ph)-2)2Cl2] 在 Na₂CO₃ 作用下， 以 丙酮 为溶剂， 以93%的产率得到cis-[Pd(py(SCHC(O)Ph)-2)2]
  参考文献：
  名称：

  Multidonor Ligands. 3. Cyclopalladation of py{SCH₂C(O)R}-2 (py-2 = 2-pyridyl, R = Ph, Me, OMe) through a C(sp³)−H Bond Activation

  摘要：

  [PdCl2(NCPh)(2)] reacts with R-carbonylmethylenethiopyridines [py{SCH2C(O)R}-2] to give, depending on the substituent R and the reaction conditions, [Pd{py{SCHC(O)Ph}-2}(mu-Cl)(2)Pd-{py{SCH2C(O)Ph}-2}Cl] or the coordination complexes [Pd{py{SCH2C(O)R}-2}(2)Cl-2] (R = Ph, Me, OMe). The latter can be doubly deprotonated by a base (Na2CO3 or NaH) to give dicyclometalated complexes cis-[Pd{py{SCHC(O)R}-2}(2)]. These transmetalate one ligand to [PdCl2(NCPh)(2)] to give [Pd{py(SCHC(O)R}-2}(mu-Cl)](2), which in turn reacts with (Me4N)Cl or with monodentate ligands L or with MeCN in the presence of AgClO4 to give anionic Me4N[Pd{py{SCHC(O)Ph}-2}Cl-2], neutral [Pd{py(SCHC(O)R}-2}Cl(L)] [R = Ph, L = PPh3, py{SCH2C(O)Ph}-2, (BuNC)-Bu-t, NH2CH(Me)Ph, pyridine (py), tetrahydrothiophene (tht); R= Me, L = PPh3, py, tht], or cationic [Pd{py{SCHC(O)R}-2}(NCMe)(2)]ClO4 (R = Ph, Me, OMe) complexes, respectively. The latter react with PPh3 or with bidentate ligands to give complexes [Pd{py{SCHC(O)Ph}-2}(NCMe)(PPh3)]ClO4 or [Pd(py{SCHC(O)Ph}-2}L-2]ClO4 [L = PPh3, L-2 = N,N,N',N'-tetramethylethylenediamine (tmeda) or 2,2'-bipyridine (bipy)]. The crystal structures of [Pd{py{SCHC(O)R}-2}(2)] and [Pd{py{SCHC(O)R}-2}Cl{py{SCH2C(O)R}2}] have been determined.

  DOI：

  10.1021/om981043f
• 作为产物：
  描述：

  二(氰基苯)二氯化钯 、 1-phenyl-2-(pyridin-2-ylthio)ethan-1-one 以 丙酮 为溶剂， 以100%的产率得到[Pd(py(SCH2C(O)Ph)-2)2Cl2]
  参考文献：
  名称：

  Multidonor Ligands. 3. Cyclopalladation of py{SCH₂C(O)R}-2 (py-2 = 2-pyridyl, R = Ph, Me, OMe) through a C(sp³)−H Bond Activation

  摘要：

  [PdCl2(NCPh)(2)] reacts with R-carbonylmethylenethiopyridines [py{SCH2C(O)R}-2] to give, depending on the substituent R and the reaction conditions, [Pd{py{SCHC(O)Ph}-2}(mu-Cl)(2)Pd-{py{SCH2C(O)Ph}-2}Cl] or the coordination complexes [Pd{py{SCH2C(O)R}-2}(2)Cl-2] (R = Ph, Me, OMe). The latter can be doubly deprotonated by a base (Na2CO3 or NaH) to give dicyclometalated complexes cis-[Pd{py{SCHC(O)R}-2}(2)]. These transmetalate one ligand to [PdCl2(NCPh)(2)] to give [Pd{py(SCHC(O)R}-2}(mu-Cl)](2), which in turn reacts with (Me4N)Cl or with monodentate ligands L or with MeCN in the presence of AgClO4 to give anionic Me4N[Pd{py{SCHC(O)Ph}-2}Cl-2], neutral [Pd{py(SCHC(O)R}-2}Cl(L)] [R = Ph, L = PPh3, py{SCH2C(O)Ph}-2, (BuNC)-Bu-t, NH2CH(Me)Ph, pyridine (py), tetrahydrothiophene (tht); R= Me, L = PPh3, py, tht], or cationic [Pd{py{SCHC(O)R}-2}(NCMe)(2)]ClO4 (R = Ph, Me, OMe) complexes, respectively. The latter react with PPh3 or with bidentate ligands to give complexes [Pd{py{SCHC(O)Ph}-2}(NCMe)(PPh3)]ClO4 or [Pd(py{SCHC(O)Ph}-2}L-2]ClO4 [L = PPh3, L-2 = N,N,N',N'-tetramethylethylenediamine (tmeda) or 2,2'-bipyridine (bipy)]. The crystal structures of [Pd{py{SCHC(O)R}-2}(2)] and [Pd{py{SCHC(O)R}-2}Cl{py{SCH2C(O)R}2}] have been determined.

  DOI：

  10.1021/om981043f