boraneyldiethoxy(methyl)-l5-phosphane | 1070805-86-5

• 英文名称: boraneyldiethoxy(methyl)-l5-phosphane
• CAS: 1070805-86-5
• 化学式: C₅H₁₆BO₂P
• 分子量: 149.966
• InChiKey: TZKPSNHPUHZWGY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为反应物：
  描述：

  boraneyldiethoxy(methyl)-l5-phosphane 、 苯基膦酸二乙酯 在 lithium diisopropyl amide 作用下， 以 四氢呋喃 为溶剂， 反应 6.0h， 以71%的产率得到diethoxy 1-(ethyl phenylphosphinate)methylphosphanyl-borane
  参考文献：
  名称：

  The phosphorus-Claisen condensation

  摘要：

  1,1-Bisphosphorus compounds are easily synthesized through the phosphorus-Claisen (phospha-Claisen) condensation between a phosphorus-stabilized anion and a phosphorus electrophile. The preliminary scope of this reaction is investigated in terms of employable phosphorus reagents. Valuable intermediates are conveniently prepared in a single step. Overall, the method is competitive with multistep procedures which require the preparation of PCI intermediates derived from the P(OR) reagents we instead employ directly, and it delivers complex organophosphorus compounds in moderate to good isolated yields. An example of the intramolecular version of the reaction, the phospha-Dieckmann condensation, is also reported. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2012.11.119