3-phenacyl-8-S-thiomethyl-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene | 1269636-23-8

• 英文名称: 3-phenacyl-8-S-thiomethyl-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene
• CAS: 1269636-23-8
• 化学式: C₁₈H₁₅BF₂N₂OS
• 分子量: 356.204
• InChiKey: SBXIQWKKXYFXPJ-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  [2-[(甲硫基)(2H-吡咯-2-亚基)甲基]-1H-吡咯](二氟硼烷) 、 2-溴苯乙酮 在 1,8-二氮杂双环[5.4.0]十一碳-7-烯 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 0.25h， 以65%的产率得到3-phenacyl-8-S-thiomethyl-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene
  参考文献：
  名称：

  Vicarious Nucleophilic Substitution of α-Hydrogen of BODIPY and Its Extension to Direct Ethenylation

  摘要：

  Direct, oxidizer-free substitution of the 3-hydrogen of BODIPY derivatives has been established through a vicarious nucleophilic substitution procedure. This methodology has been combined with a reversible Michael addition on nitrostyrenes to provide a novel, highly efficient entry to the valuable 3-styrylated BODIPY dyes.

  DOI：

  10.1021/ol200148u