Tris(2-imidazolyl)carbinol,Trihydrochlorid | 67319-08-8

• 英文名称: Tris(2-imidazolyl)carbinol,Trihydrochlorid
• 英文别名: tris(2-imidazolyl)carbinol hydrochloric salt；2-TIC*3HCl
• CAS: 67319-08-8
• 化学式: C₁₀H₁₀N₆O*3ClH
• 分子量: 339.612
• InChiKey: SJUXBZOCRCUCBX-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  cobalt(II) nitrate hexahydrate 、 Tris(2-imidazolyl)carbinol,Trihydrochlorid 在 NaOH 作用下， 以 甲醇 为溶剂， 以56.9%的产率得到bis[tris(2-imidazolyl)carbinol]cobalt(II) nitrate
  参考文献：
  名称：

  Imidazole-based nickel(II) and cobalt(II) coordination complexes for potential use as models for histidine containing metalloproteins

  摘要：

  It has been established that small molecule model complexes have been useful in studying more complex biological systems of metalloproteins. Because many metalloproteins have active sites that contain multiple histidine residues bound to a metal center, a series of imidazole-containing scorpionate ligands and the associated Co and Ni complexes have been developed to investigate the bonding parameters of histidine containing active sites. The tris(2-imidazolyl) carbinol (2-TIC, 6) and tris[2-(N-methylimidazolyl)] carbinol (2-(TIC)-T-Mc, 7) complexes of Ni2+ and Co2+, namely [Co(2-(TIC)-T-Me)(2)]Cl-2 (8), [Co(2-(TIC)-T-Me)(2)](NO3)(2) (9), [Ni(2-(TIC)-T-Me)(2)]Cl-2 (10), [Ni(2-(TIC)-T-Me)(2)] (NO3)(2) (11), [Co(2-TIC)(2)](NO3)(2) (12), and [Ni(2-TIC)(2)](NO3)(2) (13), have been prepared from the reaction of the appropriate ligand and appropriate metal salt in polar solvent. These complexes have been characterized by single crystal X-ray diffraction, spectroscopic techniques, and magnetic susceptibility. In each solid-state structure the metal center in the cation coordinates to three N atoms from two ligands and adopts a pseudo-octahedral coordination geometry. The X-ray characterization of tris[2-(N-methylimidazolyl)] carbinol is also reported. (c) 2007 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2007.03.007