| 158240-00-7

• CAS: 158240-00-7
• 化学式: C₁₄H₂₇CrN₂OSi
• 分子量: 319.463
• InChiKey: FMCFBVXJWLHTMP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  哌啶 、 、 (三甲基硅基)甲基氯化镁 在 碘甲烷 作用下， 以 四氢呋喃 、 乙醚 为溶剂， 以30%的产率得到
  参考文献：
  名称：

  Alkyl-for-Iodide Metathesis Initiated by Dissociation of the Phosphine Ligand from CpCr(NO)(PPh3)I

  摘要：

  The alkyl-for-iodide metathesis reaction that occurs when CpCr(NO)(PPh(3))I (1) is treated with 2 equiv of Me(3)SiCH(2)MgCl in THF to form CpCr(NO)(PPh(3))(CH(2)SiMe(3)) (6) has been investigated in some detail. The conversion is initiated by loss of the phosphine ligand from the chromium atom's coordination sphere, the most compelling evidence for this step being that addition of excess phosphine (e.g. 4 equiv) to the initial reaction mixture completely inhibits the reaction. Four intermediate complexes which are formed sequentially on the reaction path from 1 to 6 have been detected by IR and ESR spectroscopy. These complexes have been identified as CpCr(NO)(THF)I (2), CpCr-(NO-->Mg{CH(2)SiMe(3)})Cl)(THF)I (3), CpCr(NO-->Mg{CH(2)SiMe(3)}Cl)(THF)(CH(2)SiMe(3)) (4), and CpCr(NO) (THF)(CH(2)SiMe(3)) (5). Complexes 3 and 4 have also been detected spectroscopically during the reaction of CpCr(NO)(THF)I (2) with Me(3)SiCH(2)MgCl which produces CpCr(NO)(THF)(CH(2)SiMe(3)) (5). This understanding of the mechanistic pathway has resulted in the development of a general synthetic route to previously inaccessible 17-valence-electron CpCr(NO)(L)R complexes (L = C5H11N Or NH(2)CMe(3), R = CH(2)SiMe(3); L = C5H11N, R = CH(2)Ph).

  DOI：

  10.1021/ja00096a029