RuCl2(DMSO)2(ethylenediamine) | 90698-14-9

• 英文名称: RuCl2(DMSO)2(ethylenediamine)
• 英文别名: RuCl2(DMSO)2(en)
• CAS: 90698-14-9；954109-49-0
• 化学式: C₆H₂₀Cl₂N₂O₂RuS₂
• 分子量: 388.345
• InChiKey: NMNAIAOVBSZSNG-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  dichlorotetrakis(dimethylsulfoxide)ruthenium(II) 、 乙二胺 以 乙醇 为溶剂， 生成 RuCl2(DMSO)2(ethylenediamine)
  参考文献：
  名称：

  Hydrolytic cleavage of Schiff bases by [RuCl2(DMSO)4]

  摘要：

  New hexa-coordinated Ru(II) complexes of the type [RuCl2(DMSO)(2)(diamine)] (diamine = o-phenylenediamine and ethylenediamine) have been prepared by reacting cis-[RuCl2(DMSO)(4)] with Schiff bases (H(2)sal-en, 1; H,nap-en, 2; H(2)sal-o-pdn, 3; H(2)nap-o-pdn, 4) in a 1:1 ratio. The ligands, which were expected to act as tetradentate (N2O2) chelates under the normal reaction conditions, were found to undergo hydrolytic cleavage to form the diamine and the corresponding aldehyde. All the complexes have been characterized by analytical and spectroscopic (IR, electronic and(1)H NMR) data. Single-crystal X-ray analysis of the complex [RUCl2(DMSO)(2)(o-pndn)] revealed that the coordination environment around the ruthenium metal consists of a N2S2Cl2 octahedron. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2007.05.055

文献信息

• New half sandwich-type Ru(ii) coordination compounds characterized by the fac-Ru(dmso-S)3 fragment: influence of the face-capping group on the chemical behavior and in vitro anticancer activity
  作者：Ioannis Bratsos、Camilla Simonin、Ennio Zangrando、Teresa Gianferrara、Alberta Bergamo、Enzo Alessio

  DOI：10.1039/c1dt11043h

  日期：——

  from the universal Ru(II)-dmso precursor cis-[RuCl2(dmso)4] (P1). These complexes, that were fully characterized in solution and in the solid state, are structurally similar to the anticancer organometallic compounds [Ru(η6-arene)(chel)Cl][PF6]n but, in place of a face-capping arene, have the fac-Ru(dmso-S)3 fragment. In contrast to what observed for the corresponding arene compounds, that rapidly hydrolyze

  发现Ru（II）配合物fac- [RuCl（dmso-S）3（dmso-O）2 ] [PF 6 ]（P2）是制备半成品夹心型化合物的简便方法的极好前体的公式fac- [RuCl（dmso-S）3（N）2 ] [PF 6 ]（例如（N）2 =1,2-二氨基乙烷（en，4），反式-1,2-二氨基环己烷（dach，5）或2NH 3（6））。通式为fac- [RuCl（dmso-S）3（N – O）]的中性半夹心型化合物最好，其中N – O为阴离子螯合配体（例如N – O =吡啶甲酸（pic，7））由通用Ru（II）-dmso前体顺式[[RuCl 2（dmso）4 ]（P1）制备。这些配合物，其被充分表征在溶液中和在固态下，在结构上类似于所述抗癌有机金属化合物的[Ru（η 6 -arene）（CHEL）CL] [PF6 ] n，但是具有fac -Ru（dmso-S） 3片段，而不是覆盖面部的芳烃。