bis(2-(furan-2-carbonyl)hydrazineyl)palladium(IV) chloride | 1480657-87-1

• 英文名称: bis(2-(furan-2-carbonyl)hydrazineyl)palladium(IV) chloride
• CAS: 1480657-87-1
• 化学式: C₁₀H₁₂Cl₂N₄O₄Pd
• 分子量: 429.556
• InChiKey: IKPUKKHCDKTVNH-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  2-呋喃甲酰肼 、 potassium tetrachloropalladate(II) 反应 24.0h， 以91%的产率得到bis(2-(furan-2-carbonyl)hydrazineyl)palladium(IV) chloride
  参考文献：
  名称：

  A New Complex of Palladium(II) With 2-Furoic Hydrazide: Synthesis, Characterization, Theoretical Calculations and Biological Studies

  摘要：

  A new complex of palladium was isolated with 2-furoic hydrazide (FH) and characterized by spectroscopic methods. The results show that the ligand is coordinated to palladium by the basic nitrogen of NH2 group and has a general structure of type cis-[Pd(FH)(2)Cl-2]. The structure of palladium(II) complex was optimized and theoretical data show good agreement with the experimental results. The cytotoxic activity was evaluated in a chronic myelogenous leukemia cell line, which revealed that the compound is less active than cisplatin or carboplatin. At 300 mu g mL(-1), the complex presented antimicrobial activity more efficient than ampicillin, chloranfenicol and kanamicyn.

  DOI：

  10.5562/cca2151