[(Me3Si)2CHZn(μ-bis(2-pyridylmethyl)amine)]2 | 1021397-09-0

• 英文名称: [(Me3Si)2CHZn(μ-bis(2-pyridylmethyl)amine)]2
• CAS: 1021397-09-0
• 化学式: C₃₈H₆₂N₆Si₄Zn₂
• 分子量: 846.072
• InChiKey: ONWKVIGBGLJKRB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为反应物：
  描述：

  [(Me3Si)2CHZn(μ-bis(2-pyridylmethyl)amine)]2 、 水 以 甲苯 为溶剂， 生成 [((Me3Si)2CHZn)2(μ-OH)(μ-bis(2-pyridylmethyl)amine)]
  参考文献：
  名称：

  Mechanistic studies on the hydrolysis of a dimeric alkylzinc bis(2-pyridylmethyl)amide

  摘要：

  Bis(2-pyridylmethyl) amine 7 reacts with selected dialkylzinc compounds to give dimeric alkylzinc bis(2-pyridylmethyl) amides 8. Regardless of the steric bulk of the alkyl substituent, dimers with central Zn2N2 rings are formed. Compounds 8 undergo spontaneous hydrolysis reactions upon exposure to air/moisture which can be partially controlled if the alkyl substituent R is bulky enough [R=CH(SiMe3)(2)]. A dimeric compound 9 containing both zinc-alkyl substituents and a l-OH functionality results. In the course of this reaction, an amide instead of the expected RH is eliminated. Extensive DFT calculations show that the facile formation of a three-centered Zn[mu(HO center dot center dot center dot H center dot center dot center dot NHR)] Zn functionality is a crucial step. Further evidence for the importance of Zn[mu-(X center dot center dot center dot H center dot center dot center dot Y)]Zn intermediates (X, Y = O and now N) in the general mechanism of hydrolysis catalyzed by binuclear zinc compounds is thus provided. (C) 2007 Elsevier B. V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2007.12.013
• 作为产物：
  描述：

  bis(bis(trimethylsilyl)methyl)zinc 、 二甲基吡啶胺 以 甲苯 为溶剂， 以30%的产率得到[(Me3Si)2CHZn(μ-bis(2-pyridylmethyl)amine)]2
  参考文献：
  名称：

  Mechanistic studies on the hydrolysis of a dimeric alkylzinc bis(2-pyridylmethyl)amide

  摘要：

  Bis(2-pyridylmethyl) amine 7 reacts with selected dialkylzinc compounds to give dimeric alkylzinc bis(2-pyridylmethyl) amides 8. Regardless of the steric bulk of the alkyl substituent, dimers with central Zn2N2 rings are formed. Compounds 8 undergo spontaneous hydrolysis reactions upon exposure to air/moisture which can be partially controlled if the alkyl substituent R is bulky enough [R=CH(SiMe3)(2)]. A dimeric compound 9 containing both zinc-alkyl substituents and a l-OH functionality results. In the course of this reaction, an amide instead of the expected RH is eliminated. Extensive DFT calculations show that the facile formation of a three-centered Zn[mu(HO center dot center dot center dot H center dot center dot center dot NHR)] Zn functionality is a crucial step. Further evidence for the importance of Zn[mu-(X center dot center dot center dot H center dot center dot center dot Y)]Zn intermediates (X, Y = O and now N) in the general mechanism of hydrolysis catalyzed by binuclear zinc compounds is thus provided. (C) 2007 Elsevier B. V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2007.12.013