[{RhCl(COD)}₂(μ-THDP)] | 1137141-08-2

• 英文名称: [{RhCl(COD)}₂(μ-THDP)]
• 英文别名: [{RhCl(COD)}₂(μ-tris(1,2-dimethylhydrazino)diphosphine)]；[[RhCl(η4-cod)]2(μ-THDP)]；[[RhCl(η4-cod)]2(μ-tris(1,2-dimethylhydrazino)diphosphane)]
• CAS: 1137141-08-2
• 化学式: C₂₂H₄₂Cl₂N₆P₂Rh₂
• 分子量: 729.28
• InChiKey: YPIKMJYKYDHAEO-NBUQNDOHSA-L

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  tris(1,2-dimethylhydrazino)diphosphane 、 chloro(1,5-cyclooctadiene)rhodium(I) dimer 以 二氯甲烷 为溶剂， 以95%的产率得到[{RhCl(COD)}₂(μ-THDP)]
  参考文献：
  名称：

  在水性介质中开发 Kharasch 反应：包含桥笼配体三（1,2-二甲基肼）二膦的双核第 8 和第 9 族催化剂

  摘要：

  双核配合物 [{RuCl2(η6-p-cymene)}2(μ-THDP)] (4) 和 [{MCl(η4-cod)}2(μ-THDP)] [M = Rh (5), Ir (6)] 含有桥笼型配体三（1,2-二甲基肼基）二膦（THDP），通过处理二聚体 [{RuCl(μ-Cl)( η6-p-cymene)}2] (1) 和 [{M(μ-Cl)(η4-cod)}2] [M = Rh (2), Ir (3)] 与一当量的 THDP。(η6-芳烃)钌(II)衍生物4的结构已经通过X射线衍射方法明确证实。已发现所有这些配合物都是在温和条件（室温）下，在非均相水性介质中，溴三氯甲烷与烯烃的原子转移自由基加成反应（Kharasch 反应）的活性催化剂。（© Wiley-VCH Verlag GmbH & Co. KGaA， 69451 魏因海姆，德国，2008）

  DOI：

  10.1002/ejic.200701132

文献信息

• Exploring Rhodium(I) Complexes [RhCl(COD)(PR₃)] (COD = 1,5-Cyclooctadiene) as Catalysts for Nitrile Hydration Reactions in Water: The Aminophosphines Make the Difference
  作者：Eder Tomás-Mendivil、Rocío García-Álvarez、Cristian Vidal、Pascale Crochet、Victorio Cadierno

  DOI：10.1021/cs500241p

  日期：2014.6.6

  Several rhodium(I) complexes, [RhCl(COD)-(PR3)], containing potentially cooperative phosphine ligands, have been synthesized and evaluated as catalysts for the selective hydration of organonitriles into amides in water. Among the different phosphines screened, those of general composition P(NR2)(3) led to the best results. In particular, complex [RhCl(COD)P(NMe2)(3)}] was able to promote the selective hydration of a large range of nitriles in water without the assistance of any additive, showing a particularly high activity with heteroaromatic and heteroaliphatic substrates. Employing this catalyst, the antiepileptic drug rufinamide was synthesized in high yield by hydration of 4-cyano-1-(2,6-difluorobenzyl)-1H-1,2,3-triazole. For this particular transformation, complex [RhCl(COD)P(NMe2)(3)}] resulted more effective than related ruthenium catalysts.