5-[2-[4-(2,6-Dimethylpyridin-4-yl)-2-ethylpyridin-3-yl]ethynyl]-6-methylpyridin-2-amine | 1253055-54-7

• 英文名称: 5-[2-[4-(2,6-Dimethylpyridin-4-yl)-2-ethylpyridin-3-yl]ethynyl]-6-methylpyridin-2-amine
• CAS: 1253055-54-7
• 化学式: C₂₂H₂₂N₄
• 分子量: 342.443
• InChiKey: ABNIDWHBBSGUDX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  26
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  64.7
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• [EN] 5-ALKYNYL-PYRIDINES<br/>[FR] 5-ALCYNYLPYRIDINES
  申请人：BOEHRINGER INGELHEIM INT

  公开号：WO2010122069A1

  公开（公告）日：2010-10-28

  The present invention encompasses compounds of general Formula (I), wherein R1 to R4, m and n are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and the use thereof for preparing a medicament having the above-mentioned properties.

  本发明涵盖了一般式(I)的化合物，其中R1至R4、m和n的定义如权利要求书中所述，适用于治疗以细胞过度或异常增殖为特征的疾病，并用于制备具有上述特性的药物。
• 5-ALKYNYL-PYRIDINES
  申请人：Wunberg Tobias

  公开号：US20110098275A1

  公开（公告）日：2011-04-28

  The present invention encompasses compounds of general formula (1) wherein R 1 to R 4 , m and n are defined as in the specification, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and the use thereof for preparing a medicament having the above-mentioned properties.

  本发明涵盖了通式（1）中定义的化合物，其中R1至R4，m和n如规范中所定义，适用于治疗由过度或异常细胞增殖特征的疾病，并且可以用于制备具有上述特性的药物。
• US9090564B2
  申请人：——

  公开号：US9090564B2

  公开（公告）日：2015-07-28