(HOC17H7N3(O)2)PtCl(dimethyl sulfoxide) | 937380-56-8

• 英文名称: (HOC17H7N3(O)2)PtCl(dimethyl sulfoxide)
• CAS: 937380-56-8
• 化学式: C₁₉H₁₄ClN₃O₄PtS
• 分子量: 610.937
• InChiKey: VDMAWIPCWQDRBR-UHFFFAOYSA-L

反应信息

• 作为反应物：
  描述：

  3-羟基-6-甲基吡啶 、 (HOC17H7N3(O)2)PtCl(dimethyl sulfoxide) 以 二氯甲烷 为溶剂， 生成 (HOC17H7N3(O)2)PtCl(5-hydroxy-2-methylpyridine)
  参考文献：
  名称：

  Platinum Complex as a Nanomolar Protein Kinase Inhibitor

  摘要：

  A pyridocarbazole platinum complex, which matches the overall shape of the natural product staurosporine, binds with high affinity at the adenosine triphosphate binding site of glycogen synthase kinase 3 (GSK-3 alpha).

  DOI：

  10.1021/ic062055t
• 作为产物：
  描述：

  ((tert-butyldimethylsilyl)OC17H6N3(O)2(tert-butyldimethylsilyl))PtCl(dimethyl sulfoxide) 在 四丁基氟化铵 作用下， 以 二氯甲烷 为溶剂， 生成 (HOC17H7N3(O)2)PtCl(dimethyl sulfoxide)
  参考文献：
  名称：

  Platinum Complex as a Nanomolar Protein Kinase Inhibitor

  摘要：

  A pyridocarbazole platinum complex, which matches the overall shape of the natural product staurosporine, binds with high affinity at the adenosine triphosphate binding site of glycogen synthase kinase 3 (GSK-3 alpha).

  DOI：

  10.1021/ic062055t