sec.-Butyl-(2-methylphenyl)-ether | 51241-45-3

• 英文名称: sec.-Butyl-(2-methylphenyl)-ether
• 英文别名: (2-Methylphenyl)-(1-methylpropyl)-ether；1-Butan-2-yloxy-2-methylbenzene
• CAS: 51241-45-3
• 化学式: C₁₁H₁₆O
• 分子量: 164.247
• InChiKey: SYYFHOGBGDFKFA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  6-acetoxy-2,6-dimethyl-2,4-cyclohexadienone 以46%的产率得到
  参考文献：
  名称：

  MILLER B., J. ORG. CHEM. , 1977, 42, NO 8, 1402-1408

  摘要：

  DOI：

文献信息

• BICYCLIC DERIVATIVES AS MODULATORS OF VOLTAGE GATED ION CHANNELS
  申请人：Vertex Pharmaceuticals Incorporated

  公开号：US20130131109A1

  公开（公告）日：2013-05-23

  Bicyclic derivatives useful as ion channel antagonists are disclosed herein. The compositions thereof are useful for treating or relieving pain-related conditions.

  本文披露了作为离子通道拮抗剂有用的双环衍生物。其组合物对于治疗或缓解与疼痛有关的疾病是有用的。
• MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS
  申请人：Mochida Pharmaceutical Co., Ltd.

  公开号：EP2473491B1

  公开（公告）日：2013-07-17
• 5 HT RECEPTOR MEDIATED NEUROGENESIS
  申请人：Barlow Carrolee

  公开号：US20100009983A1

  公开（公告）日：2010-01-14

  The instant disclosure describes methods for treating diseases and conditions of the central and peripheral nervous system by stimulating or increasing neurogenesis. The disclosure includes compositions and methods based on use of a 5HTR agent, in combination with one or more other neurogenic agents, or anti-astrogenic agent, to stimulate or activate the formation of new nerve cells.
• MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR
  申请人：Miller Mark Thomas

  公开号：US20170196862A2

  公开（公告）日：2017-07-13

  The present invention features a compound of formula I: or a pharmaceutically acceptable salt thereof, where R 1 , R 2 , R 3 , W, X, Y, Z, n, o, p, and q are defined herein, for the treatment of CFTR mediated diseases, such as cystic fibrosis. The present invention also features pharmaceutical compositions, method of treating, and kits thereof.