| 200216-08-6

• CAS: 200216-08-6
• 化学式: C₁₅H₁₇N₃O₄
• 分子量: 303.318
• InChiKey: VZUCENSPVSBSNM-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  在 溶剂黄146 作用下， 反应 2.0h， 以32%的产率得到
  参考文献：
  名称：

  Synthesis of Mesomeric Betaines, Quinoliziniumides, via Back-donated 1,6-Cyclization

  摘要：

  The reaction of 3-aminopyridinium salts (4) with polarized olefins (2a,b, 3) in the presence of triethylamine yielded the corresponding 3-aminopyridinium N-allylides (5). Thermolysis of 3-aminopyridinium N-allylides (5a-c,h-j,l-n) in refluxing xylene afforded the 1,5-dipolar cyclization products, 8-aminoindolizines (6) together with the back-donated 1,6-cyclization products, quinoliziniumides (7). In addition, thermolysis of N-allylides (5a-c,h-j,l-n) in refluxing AcOH gave quinoliziniumides (7).

  DOI：

  10.3987/com-97-7948
• 作为产物：
  描述：

  乙氧基甲叉丙二酸二乙酯 、 3-amino-1-(cyanomethyl)pyridinium chloride 在 三乙胺 作用下， 以 乙醇 为溶剂， 反应 5.0h， 以32%的产率得到
  参考文献：
  名称：

  Synthesis of Mesomeric Betaines, Quinoliziniumides, via Back-donated 1,6-Cyclization

  摘要：

  The reaction of 3-aminopyridinium salts (4) with polarized olefins (2a,b, 3) in the presence of triethylamine yielded the corresponding 3-aminopyridinium N-allylides (5). Thermolysis of 3-aminopyridinium N-allylides (5a-c,h-j,l-n) in refluxing xylene afforded the 1,5-dipolar cyclization products, 8-aminoindolizines (6) together with the back-donated 1,6-cyclization products, quinoliziniumides (7). In addition, thermolysis of N-allylides (5a-c,h-j,l-n) in refluxing AcOH gave quinoliziniumides (7).

  DOI：

  10.3987/com-97-7948