8-quinolinecarboxaldehyde selenosemicarbazonato-N,N,Se-chloroplatinum(II) | 1600515-96-5

• 英文名称: 8-quinolinecarboxaldehyde selenosemicarbazonato-N,N,Se-chloroplatinum(II)
• CAS: 1600515-96-5
• 化学式: C₁₁H₉ClN₄PtSe
• 分子量: 506.712
• InChiKey: HQKXZKNJSRGQHS-MOEKMLTRSA-L

反应信息

• 作为产物：
  描述：

  potassium tetrachloroplatinate(II) 、 8-quinolinecarboxaldehyde selenosemicarbazone 以 二甲基亚砜 为溶剂， 反应 1.0h， 以76.7%的产率得到8-quinolinecarboxaldehyde selenosemicarbazonato-N,N,Se-chloroplatinum(II)
  参考文献：
  名称：

  Biological activity of two isomeric N-heteroaromatic selenosemicarbazones and their metal complexes

  摘要：

  New square-planar Pd(II) and Pt(II) complexes with 8-quinolinecarboxaldehyde selenosemicarbazone have been synthesized and characterized by use of elemental analysis, molar conductivity measurements, and IR and NMR spectroscopy. The cytotoxic activity of the ligand, new Pt(II) and Pd(II) compounds, and previously synthesized Pd(II), Pt(II), Cd(II), and Ni(II) complexes with the analogous ligand, 2-quinolinecarboxaldehyde selenosemicarbazone, was tested against two human cancer cell lines: lung carcinoma (H460) and glioma (U251). The potential of these compounds to induce perturbations of the H460 cell cycle was also evaluated. These substances had an excellent radical-scavenging effect against ABTS radical cations. The best antimicrobial activity, among two yeasts and eight bacterial strains tested, was against Bacillus cereus.

  DOI：

  10.1007/s00706-014-1197-6