| 170891-71-1

• CAS: 170891-71-1
• 化学式: C₄₅H₄₀IrN₂P₂*F₆Sb
• 分子量: 1098.73
• InChiKey: VUVQUNBXJVXHPQ-UHFFFAOYSA-H

反应信息

• 作为产物：
  描述：

  8-氨基喹啉 、 IrH2(PPh3)2(C3H6O)2SbF6 以 二氯甲烷 为溶剂， 以79%的产率得到
  参考文献：
  名称：

  An Unusual Coordination Mode for Amides: Lone-Pair Binding via Nitrogen

  摘要：

  A variety of 8-amino- and amido-substituted quinolines react with [Ir(PPh(3))(2)H-2(acetone)(2)]SbF6 (1) to give a series of complexes in which the amine or amide nitrogen hinds to the metal. Thp X-ray crystal structures of [Ir(H)(2)-(PPh(3))(2)(C9H6N{HNCO(t)Bu})]SbF6 (4b) and [Ir(H)(2)(PPh(3))(2)(C9H6N{HNSi(t)BuMe(2)})]SbF6 (4c) were obtained: 4b, a = 9.904(4) Angstrom, b = 13.480(5) Angstrom, c = 19.346(9) Angstrom, alpha = 83.79(4), beta = 81.64 (4)degrees, gamma = 76.52(3)degrees, Z = 2, triclinic , R = 5.37%; 4c, a = 45.24(1) Angstrom, b = 10.536(3) Angstrom, c = 25.450(7) Angstrom, beta = 111.11(2)degrees Z = 8, monoclinic R = 5.30%. The X-ray data do not allow a definite distinction between the two possible binding modes, N binding via the lone pair and N-H agostic (2e, 3-center) binding. Definitive evidence for the lone-pair-bound structure was obtained from natural-abundance N-15 heteronuclear multiple-quantum coherence (HMQC) spectroscopy and proton nuclear Overhauser effect (NOE) data. The amine or amide N therefore rehyhridizes to sp(3) on binding, a previously unreported complexation mode for undeprotonated amides that normally coordinate via. O. Fluxional exchange processes are interpreted on the basis of N lone-pair decoordination and inversion with the possible intermediacy of an agostic species or iminol tautomer. The Ir-N bond distances (4b, 2.313(9) Angstrom and 4c, 2.320(10) Angstrom) are very long. The NH of the coordinated amide is much more acidic than that of the free amide and ran be deprotonated with NEt(3) to give an N-bound complex of the deprotonated amide. In a conformationally restricted pyrrole where the N lone pair cannot bind to Ir, we find that deprotonation occurs spontaneously to give a pyrrolyl complex.

  DOI：

  10.1021/ic00129a014