| 511546-89-7

• CAS: 511546-89-7
• 化学式: C₃₂H₂₆Cl₄N₂O₄Pd₂
• 分子量: 857.221
• InChiKey: BBVFGAGLGCYGCW-IRKBQLKBSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  、 三苯基膦 以 丙酮 为溶剂， 以74%的产率得到
  参考文献：
  名称：

  Cyclopalladation of Schiff bases from phenylalanine and 2-phenylglicine

  摘要：

  The action of palladium acetate on the Schiff bases 4-ClC6H,CH=N-CH(R-2)COOR1 (R-1 = Me, Et; R-2 = Ph, CH2Ph), in acetic acid for 3 h at 70 degreesC and subsequent treatment of the reaction residues with LiCl in acetone, affords the corresponding chlorobridged five-membered endo-metallacycles [PdCl(C-N)](2), 1a, 2a. The action of palladium acetate on the Schiff bases 2,6-Cl2C6H,CH=N-CH(R-2)COOR1 (R-1 = Me, Et; R-2 = Ph, CH2Ph), in chloroform at room temperature and subsequent treatment of the reaction residues with LiCl in acetone, affords the corresponding chloro-bridged five- or six-membered exo-metallacycles, by metallation of the amino acid moiety [PdCl(C-N)](2), 3a-exo, 4a-exo. A small amount of the endo-metallacycles was also obtained, probably by oxidative addition of the ortho C-Cl bond of these immes to Pd(0) formed in situ. Reaction of dimers 1a-4a with PPh3 affords the mononuclear complexes [PdCl(C-N)(PPh3)] 1b-4b. (C) 2002 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0022-328x(02)01928-9
• 作为产物：
  描述：

  palladium diacetate 、 lithium chloride 、 2,6-Cl2C6H3CH=NCH(Ph)COOMe 以 氯仿 为溶剂， 以5%的产率得到
  参考文献：
  名称：

  Cyclopalladation of Schiff bases from phenylalanine and 2-phenylglicine

  摘要：

  The action of palladium acetate on the Schiff bases 4-ClC6H,CH=N-CH(R-2)COOR1 (R-1 = Me, Et; R-2 = Ph, CH2Ph), in acetic acid for 3 h at 70 degreesC and subsequent treatment of the reaction residues with LiCl in acetone, affords the corresponding chlorobridged five-membered endo-metallacycles [PdCl(C-N)](2), 1a, 2a. The action of palladium acetate on the Schiff bases 2,6-Cl2C6H,CH=N-CH(R-2)COOR1 (R-1 = Me, Et; R-2 = Ph, CH2Ph), in chloroform at room temperature and subsequent treatment of the reaction residues with LiCl in acetone, affords the corresponding chloro-bridged five- or six-membered exo-metallacycles, by metallation of the amino acid moiety [PdCl(C-N)](2), 3a-exo, 4a-exo. A small amount of the endo-metallacycles was also obtained, probably by oxidative addition of the ortho C-Cl bond of these immes to Pd(0) formed in situ. Reaction of dimers 1a-4a with PPh3 affords the mononuclear complexes [PdCl(C-N)(PPh3)] 1b-4b. (C) 2002 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0022-328x(02)01928-9