PdCl2(2-acetopyridine)2 | 143133-86-2

• 英文名称: PdCl2(2-acetopyridine)2
• CAS: 143133-86-2
• 化学式: C₁₄H₁₄Cl₂N₂O₂Pd
• 分子量: 419.603
• InChiKey: BEYUKIAVXVOIAM-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  2-乙酰基吡啶 、 trans-[PdCl2(PPh(C6H4Cl-2)2)2] 以 氘代氯仿 为溶剂， 以0%的产率得到PdCl2(2-acetopyridine)2
  参考文献：
  名称：

  Coupling of Aryl Halides with Aryl Boronic Acids with P(C₆H₅)(2-C₆H₄Cl)₂ as the Supporting Ligand

  摘要：

  The chlorinated triarylphosphine P(C6H5)(2-C6H4Cl)(2) (1) has been used as a supporting ligand in the Suzuki-Miyaura coupling of aryl boronic acids with aryl halides. Aryl bromides without ortho substituents were successfully coupled at room temperature, while reactions involving sterically hindered aryl bromides required slight heating (70 degreesC). Electron-deficient aryl chlorides were also successfully coupled with heating (90 degreesC). Key reaction parameters such as order of addition, choice of mineral base, solvent volume, temperature, 1/Pd ratio, as well as electronic and steric variation of the aryl halide have been investigated and are reported.

  DOI：

  10.1021/om020885i