4-amino-1-(2,4-dichlorophenacyl)-1,2,4-triazolium N-ylide | 126961-78-2

• 英文名称: 4-amino-1-(2,4-dichlorophenacyl)-1,2,4-triazolium N-ylide
• CAS: 126961-78-2
• 化学式: C₁₀H₈Cl₂N₄O
• 分子量: 271.106
• InChiKey: YLNQBBIYDNNRHH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  2-溴-2',4'-二氯苯乙酮 在 ammonium hydroxide 作用下， 以 乙腈 为溶剂， 反应 0.33h， 生成 4-amino-1-(2,4-dichlorophenacyl)-1,2,4-triazolium N-ylide
  参考文献：
  名称：

  Krimer, M. Z.; Tashi, B. P.; Roitburd, G. V., Doklady Chemistry, 1989, vol. 308, # 4-6, p. 299 - 301

  摘要：

  DOI：

文献信息

• Nitrosation of 4-amino-1-phenacyl-1,2,4-triazolium bromides and ?-(1,2,4-triazol-1-yl)acetophenones
  作者：I. M. Shtyrkov、G. V. Roitburd、V. P. Tashchi、M. Z. Krimer

  DOI：10.1007/bf00959722

  日期：1991.12

  The reaction of 4-amino-1-phenacyl-1,2,4-triazolium bromides with an excess of nitrous acid leads to a mixture of the corresponding omega-(1,2,4-triazol-1-yl)acetophenones and omega-hydroximino-omega-(1,2,4-triazol-1-yl)acetophenones. Products of the latter type are formed during nitrosation at the methylene group of both the intermediate omega-triazolylacetophenones, and the starting 4-amino-1-phenacyl-1,2,4-triazolium bromides. The role of Br- as a catalyst is significant for both nitrosation paths. In the reaction of omega-(1,2,4-triazol-1-yl)acetophenones with HNO2, SCN- is a more active catalyst than Br-. During the nitrosation of para-substituted 4-amino-1-phenacyl-1,2,4-triazolium bromides, the yield of omega-hydroximino-omega-(1,2,4-triazol-1-yl)acetophenones increases with increase in the acceptor properties of the aryl substituent, which is explained by the increase in the CH-acidity of the nitrosation substrates.