(C5Me5)W(CO)2(COOCH(Ph)CHCH2) | 220886-29-3

• 英文名称: (C5Me5)W(CO)2(COOCH(Ph)CHCH2)
• CAS: 220886-29-3
• 化学式: C₂₂H₂₄O₄W
• 分子量: 536.28
• InChiKey: JUVBSBJRGDXFLL-USOZLSCGSA-N

反应信息

• 作为产物：
  描述：

  三氟甲磺酸 、 (C5Me5)W(CO)3CH2C*CPh 以 二氯甲烷 为溶剂， 以56%的产率得到(C5Me5)W(CO)2(COOCH(Ph)CHCH2)
  参考文献：
  名称：

  New Carbonylation Reaction of Tungsten−Propargyl Compounds via Protonation at a Prolonged Period

  摘要：

  The CpW(CO)(3)(eta(1)-CH2C equivalent to CR) (R = Me 1, Ph 2) complexes were treated with triflic acid (2.0 equiv) in cold dichloromethane (-78 degrees C), and after a long period to the mixture was added water or RNH2 to give good yields of carbonylation products CpW(CO)(2)(eta(1),eta(2)-CH2-CHCHR-Y-CO-) (R = Me, Ph; Y = RN, O). These products were fully characterized by appropriate physical methods including single-crystal X-ray diffraction. If a chiral amine such as (R)-methylbenzylamine was used in the reaction, two optically active isomers in equal proportions were obtained and further separated on a silica column. In the case of (C5Me5)W(CO)(3)(eta(1)-CH2C equivalent to CPh) (9), its reactions with triflic acid and water in the same reaction sequence produce (C5Me5)W(CO)(2)(eta(1),eta(2)-CH2CHCHPh-O-CO-) as two diastereomers which undergo mutual exchange according to variable-temperature H-1 NMR spectroscopy.

  DOI：

  10.1021/om980787q