(1,2-bis(diisopropylphosphino)ethane)Ni(3-Me-Ph)Br | 1043927-35-0

• 英文名称: (1,2-bis(diisopropylphosphino)ethane)Ni(3-Me-Ph)Br
• CAS: 1043927-35-0
• 化学式: C₂₁H₃₉BrNiP₂
• 分子量: 492.082
• InChiKey: TYJPVNSBCJSTJI-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  (1,2-bis(diisopropylphosphino)ethane)Ni(3-Me-Ph)Br 、 (三氟甲基)三甲基硅烷 在 cesium fluoride 作用下， 以 四氢呋喃 为溶剂， 以54%的产率得到(1,2-bis(diisopropylphosphino)ethane)Ni(3-Me-Ph)(trifluoromethyl)
  参考文献：
  名称：

  Exploring Trifluoromethylation Reactions at Nickel: A Structural and Reactivity Study

  摘要：

  A variety of nickel(aryl)(CF3) complexes supported by a chelating bisphosphine were successfully prepared in order to investigate the possibility of reductive elimination of Ar-CF3. The first structural comparison of a Ni-CF3 complex with a Ni-CH3 complex is also presented. All of the new nickel(aryl)(CF3) complexes were thermally stable and did not produce Ar-CF3 under thermal conditions. Additives had very little effect on the reductive eliminations, although water was found to afford product in 22% yield.

  DOI：

  10.1021/om800300k
• 作为产物：
  描述：

  bis(1,5-cyclooctadiene)nickel (0) 、 3-溴甲基苯 、 1,2-双(二-异丙基膦基)乙烷 以 甲苯 为溶剂， 以74%的产率得到(1,2-bis(diisopropylphosphino)ethane)Ni(3-Me-Ph)Br
  参考文献：
  名称：

  Exploring Trifluoromethylation Reactions at Nickel: A Structural and Reactivity Study

  摘要：

  A variety of nickel(aryl)(CF3) complexes supported by a chelating bisphosphine were successfully prepared in order to investigate the possibility of reductive elimination of Ar-CF3. The first structural comparison of a Ni-CF3 complex with a Ni-CH3 complex is also presented. All of the new nickel(aryl)(CF3) complexes were thermally stable and did not produce Ar-CF3 under thermal conditions. Additives had very little effect on the reductive eliminations, although water was found to afford product in 22% yield.

  DOI：

  10.1021/om800300k