4-(diisopropylphosphino)indenyl-pentamethylcyclopentadienyliron | 938439-84-0

• 英文名称: 4-(diisopropylphosphino)indenyl-pentamethylcyclopentadienyliron
• CAS: 938439-84-0
• 化学式: C₂₅H₃₅FeP
• 分子量: 422.374
• InChiKey: ARHDSJXTMSRYTM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  (+/-)-(η5-pentamethylcyclopentadienyl)(η5-4-bromoindene)iron 、 氯二异丙基膦 在 n-BuLi or t-BuLi 作用下， 以 乙醚 、 正戊烷 为溶剂， 以78%的产率得到4-(diisopropylphosphino)indenyl-pentamethylcyclopentadienyliron
  参考文献：
  名称：

  Novel benzoferrocenyl chiral ligands: Synthesis and evaluation of their suitability for asymmetric catalysis

  摘要：

  Four benzoferrocenyl phosphorus chiral ligands were conveniently prepared in good overall yields. These ligands were found to be stable in solid form and in solution. Two of the four ligands were resolved by chiral HPLC. Unlike a reported bis(phosphino-eta(5)-indenyl)iron(II) complex, in which the indenyl ligands undergo ring flipping through an eta(1)-intermediate, these two ligands were found to be configurationally stable in solution and in solid state. The suitability of these ligands for enantioselective catalysis was assessed in studies on allylic alkylation reactions. When the two less sterically hindered ligands were used, excellent chemical yields were obtained, but the other two more sterically hindered ones gave lower yields. When the two enantiopure ligands were used, enantioselectivity of up to 51% ee was observed. These findings suggest that benzoferrocene derivatives may be used as chiral ligands for asymmetric catalysis. (c) 2007 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2007.01.004