[RhCl2(pyrazole)4][RhCl4(pyrazole)2] | 455893-78-4

• 英文名称: [RhCl2(pyrazole)4][RhCl4(pyrazole)2]
• CAS: 455893-78-4
• 化学式: C₆H₈Cl₄N₄Rh*C₁₂H₁₆Cl₂N₈Rh
• 分子量: 826.998
• InChiKey: DUOGWKCAEGKMBL-UHFFFAOYSA-H

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
  None
• 氢给体数：
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• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  吡唑 、 氯化铑(三水) 以 乙醇 为溶剂， 以33%的产率得到[RhCl2(pyrazole)4][RhCl4(pyrazole)2]
  参考文献：
  名称：

  Rhodium(III) complexes with polypyridyls and pyrazole and their antitumor activity

  摘要：

  Synthesis and properties of rhodium complexes with nitrogen ligands [RhCl2(Hpz)(4)][RhCl4(Hpz)(2)] (1), [RhCl3(tpy)] (2), [RhCl3(tpta)] . H2O (3) and [Rh(tpy)(2)(Him)]Cl-3 . 3H(2)O (4), have been described. X-ray structures of complexes 1-3 have been determined. IR, UV-Vis and H-1 NMR spectra of the complexes have been discussed. Cytostatic activity of the complexes against HCV29T tumor cells increases in the series: 1 < 3 < 2 < 4. The cytostatic activity of complex 4 is greater than that of cisplatin. Interaction of the complexes with DNA has been investigated. (C) 2002 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0020-1693(02)00776-4