| 1017803-37-0

• CAS: 1017803-37-0
• 化学式: C₂₆H₃₀Cl₃FeN₂O₆
• 分子量: 628.74
• InChiKey: WVMDWHLZUSJYEK-ZZWWLCIUSA-K

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  、 三氯化铁 以 甲醇 为溶剂， 以57%的产率得到
  参考文献：
  名称：

  Chiral 27-membered [3+3] Schiff-base macrocycles and their reactivity with first-row transition metal ions

  摘要：

  27-Membered Schiff-base macrocycles 1 and 2 are prepared via the [3 + 3] template condensation of 2,6-diformyl-4-substituted phenol (R = Cl in 1 and R = CH3 in 2) with enantiomeric [(1R,2R) or (1S,2S)] and racemic trans-cyclohexane-1,2-diamines. Among them two chiral [3 + 3] macrocyclic single-crystals (S,S)-1 and (R,R)-2 in their backbones have been structurally characterized. Both of them have triangular holes (similar to 42.36 angstrom(2)) in which one phenyl ring of the neighboring molecule is inserted as a guest by pi-pi stacking interactions with the centroid-centroid separation of 3.599 angstrom. The treatment of aforementioned macrocycles with certain first-row transition metal salts [Cu(II), Zn(II), Fe(III)] with different counterions leads to the cleavage of Schiff-base C = N double bonds and degradation of the macrocycles due to the size matching effect of macrocycles as well as the restriction of coordination geometry of the central metals and the counterions used. As a result, [2 + 2], [2 + 1] and [1 + 2] types of complexes ((R,R)-3, 4, 5 and 6) are yielded. In the case of 6, a new type of dimethyl acetal complex is produced in methanol where FeCl3 serves as a reactive Lewis acid catalyst. The intrinsic chiral differences of the macrocycles and their transition metal complexes are demonstrated by circular dichroism (CD) spectra. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2007.12.003