trans-[PtCl(NH3)2NH2(CH2)6NHBOC]NO3 | 172902-95-3

• 英文名称: trans-[PtCl(NH3)2NH2(CH2)6NHBOC]NO3
• CAS: 172902-95-3
• 化学式: C₁₁H₃₀ClN₄O₂Pt*NO₃
• 分子量: 542.923
• InChiKey: OUXYNPNRQCKWAJ-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  盐酸 、 trans-[Pt(NH3)2(H2N(CH2)6NH3)2](4+) 、 trans-[PtCl(NH3)2NH2(CH2)6NHBOC]NO3 在 sodium hydroxide 作用下， 以 甲醇 、 N,N-二甲基甲酰胺 为溶剂， 生成 TriplatinNC
  参考文献：
  名称：

  Synthesis, Characterization, and Cytotoxicity of a Novel Highly Charged Trinuclear Platinum Compound. Enhancement of Cellular Uptake with Charge

  摘要：

  Charge delocalization (6+ to 8+) in "noncovalent" linear trinuclear platinum complexes produces compounds with cytotoxicity in some cases equivalent to cisplatin. The cellular uptake of a novel 8+ compound is greater than that of neutral cisplatin as well as other multinuclear Pt compounds.

  DOI：

  10.1021/ic051390z
• 作为产物：
  描述：

  N-Boc-1,6-己二胺 、 [trans-Pt(NH₃)₂Cl]NO₃ 以 N,N-二甲基甲酰胺 为溶剂， 生成 trans-[PtCl(NH3)2NH2(CH2)6NHBOC]NO3
  参考文献：
  名称：

  Synthesis, Characterization, and Cytotoxicity of a Novel Highly Charged Trinuclear Platinum Compound. Enhancement of Cellular Uptake with Charge

  摘要：

  Charge delocalization (6+ to 8+) in "noncovalent" linear trinuclear platinum complexes produces compounds with cytotoxicity in some cases equivalent to cisplatin. The cellular uptake of a novel 8+ compound is greater than that of neutral cisplatin as well as other multinuclear Pt compounds.

  DOI：

  10.1021/ic051390z