ZnBr2(4'-(4-chlorophenyl)-2,2':6',2''-terpyridine) | 1400766-85-9

• 英文名称: ZnBr2(4'-(4-chlorophenyl)-2,2':6',2''-terpyridine)
• CAS: 1400766-85-9
• 化学式: C₂₁H₁₄Br₂ClN₃Zn
• 分子量: 569.013
• InChiKey: JLUKWFVIENVXTG-UHFFFAOYSA-L

反应信息

• 作为产物：
  描述：

  4′-(4-氯苯基)-2, 2′:6′, 2″-三联吡啶 、 zinc dibromide 以 甲醇 、 氯仿 为溶剂， 以87%的产率得到ZnBr2(4'-(4-chlorophenyl)-2,2':6',2''-terpyridine)
  参考文献：
  名称：

  Urease inhibitory activities of ZnBr2 and ZnI2 complexes of terpyridine derivatives: Systematic investigation of aryl substituents on urease inhibitory activities

  摘要：

  With the aim of discovering novel urease inhibitors, six new mononuclear complexes of five-coordinated Zn(II) bromide and iodide with terpyridine derivatives have been synthesized and their solid state structures were characterized by X-ray crystallography. Among these complexes, the zinc complexes bearing an electron withdrawing aryl group at the 4'-position show medium urease inhibitory activities, with IC50 values much lower than those of previously reported zinc species, at concentrations lower than 100 mM. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2012.07.035