rac-2,2'-bis(boranatodiethylphosphino)-3,3',4,4',5,5',6,6'-octamethyl-1,1'-biphenyl | 590362-85-9

• 英文名称: rac-2,2'-bis(boranatodiethylphosphino)-3,3',4,4',5,5',6,6'-octamethyl-1,1'-biphenyl
• CAS: 590362-85-9；590362-84-8
• 化学式: C₂₈H₅₀B₂P₂
• 分子量: 470.275
• InChiKey: FRFZRVJNFRUZPY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  Tetrahydro-furan; compound with trifluoroborane 、 S-2,2'-bis(diethylphosphonyl)-3,3',4,4',5,5',6,6'-octamethyl-1,1'-biphenyl 在 lithium aluminium tetrahydride 作用下， 以 乙二醇二甲醚 为溶剂， 以77%的产率得到rac-2,2'-bis(boranatodiethylphosphino)-3,3',4,4',5,5',6,6'-octamethyl-1,1'-biphenyl
  参考文献：
  名称：

  Preparation of an optically active bis(diethylphosphino)biphenyl ligand designed for highly reactive catalytic processes

  摘要：

  New optically active diphosphine ligands, (S)-2,2'-bis(diphenylphosphino)-3,3',4,4',5,5',6,6'-octamethylbiphenyl (2a) and (S)-2,2'-bis(diethylphosphino)-3,3',4,4',5,5',6,6'-octamethylbiphenyl (2c) were prepared via optical resolution of the corresponding phosphine oxides. The Rh complex of 2c proved efficient in the catalytic asymmetric hydrogenation of a dehydroamino acid derivative even at -50degreesC and gave 88% e.e. of hydrogenation product quantitatively. (C) 2002 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s1381-1169(02)00640-4