[Fe-η5-cyclopentadienyl(dppe)(3-quinolinecarbonitirile)][CF3SO3] | 1574678-30-0

• 英文名称: [Fe-η5-cyclopentadienyl(dppe)(3-quinolinecarbonitirile)][CF3SO3]
• 英文别名: [Fe-η⁵-cyclopentadienyl(dppe)(3-quinolinecarbonitirile)][CF₃SO₃]；[FeCp(dppe)(3-cq)][CF₃SO₃]
• CAS: 1574678-30-0
• 化学式: CF₃O₃S*C₄₁H₃₅FeN₂P₂
• 分子量: 822.607
• InChiKey: JMVZSNNTYBRBJN-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  3-氰基喹啉 、 [1,2-bis(diphenylphosphino)ethane](η5-cyclopentadienyl)iron(II) iodide 、 silver trifluoromethanesulfonate 以 二氯甲烷 为溶剂， 以80%的产率得到[Fe-η5-cyclopentadienyl(dppe)(3-quinolinecarbonitirile)][CF3SO3]
  参考文献：
  名称：

  New iron(II) cyclopentadienyl derivative complexes: Synthesis and antitumor activity against human leukemia cancer cells

  摘要：

  A new family of "Fe-II(eta(5)-C5H5)" half sandwich compounds bearing a N-heteroaromatic ligand coordinated to the iron center by a nitrile functional group has been synthesized and fully characterized by NMR and UV-Vis spectroscopy. X-ray analysis of single crystal was achieved for complexes 1 and 3, which crystallized in the monoclinic P2(1)/c and monoclinic P2(1)/n space groups, respectively. Studies of interaction of these five new complexes with plasmid pBR322 DNA by atomic force microscopy showed very strong and different types of interaction. Antiproliferative tests were examined on human leukemia cancer cells (HL-60) using the MTT assay, and the IC50 values revealed excellent antiproliferative activity compared to cisplatin. (C) 2014 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2014.01.027