[Ru(III)Cl4(DMSO)(N(6)-butyladeninium)] | 873310-01-1

• 英文名称: [Ru(III)Cl4(DMSO)(N(6)-butyladeninium)]
• CAS: 873310-01-1
• 化学式: C₁₁H₂₀Cl₄N₅ORuS
• 分子量: 513.261
• InChiKey: WYYIQHXQILGWTR-UHFFFAOYSA-K

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  (DMSO)2H[trans-RuCl4(DMSO)2] 、 6-n-butylaminopurine 以 盐酸 、 乙醇 为溶剂， 以40%的产率得到[Ru(III)Cl4(DMSO)(N(6)-butyladeninium)]
  参考文献：
  名称：

  Ruthenium complexes with purine derivatives: Syntheses, structural characterization and preliminary studies with plasmidic DNA

  摘要：

  Two new chloride-dimethylsulfoxide-ruthenium(III) complexes, [(RuCl4)-Cl-III(DMSO)(H-Hypoxanthine)] (1) and [Ru-III Cl-4 (DMSO)[H-(N-6-butyladenine)]] (2), have been prepared and structurally characterized by X-ray diffraction crystallography. The Ru(III)-hypoxanthine complex 1 is the first complex where monodentate coordination of hypoxanthine through nitrogen N(3) has been observed.Preliminary electrophoretic mobility and atomic force microscopy (AFM) studies show that both compounds interact with plasmidic DNA but the nature of the nucleobase seems to be important. (c) 2005 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.inoche.2005.05.023