cis(C,N)-chloromethyl(dimethyl sulfoxide)(2-chloropyridine)platinum(II) | 185226-16-8

• 英文名称: cis(C,N)-chloromethyl(dimethyl sulfoxide)(2-chloropyridine)platinum(II)
• CAS: 185226-16-8；185043-08-7
• 化学式: C₈H₁₃Cl₂NOPtS
• 分子量: 437.249
• InChiKey: OLMCMHBOYPUTRG-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  2-氯吡啶 、 trans-[PtMeCl(dmso)₂] 以 氘代氯仿 为溶剂， 生成 cis(C,N)-chloromethyl(dimethyl sulfoxide)(2-chloropyridine)platinum(II)
  参考文献：
  名称：

  trans-Chloromethylbis(dimethyl sulfoxide)platinum(II):  X-ray Structure, Mechanism of Isomerization, and Its Use as a Precursor to Organoamine Complexes of Variable Geometrical Configurations

  摘要：

  An unusual 2:1 aggregate between the complex trans-[PtCl(CH3)(DMSO)(2)] (1; DMSO = dimethyl sulfoxide) and the organotin compound bis(mu(3)-oxo)bis(mu-chloro)bis(mu-dimethyltin(IV))bis(chlorodimethyltin(IV)) [Cl(CH3)(2)-SnOSn(CH3)(2)Cl](2) has been isolated and characterized by X-ray analysis. The crystals belong to the triclinic space group with lattic constants a = 9.373(2) Angstrom, b = 9.576(1) Angstrom, c = 14.087(3) Angstrom, alpha = 70.29(1), beta = 75.50(1)degrees, gamma = 72.21(2)degrees, and Z = 2. Least-squares refinement of the structure led to an R factor of 2.37%. H-1, C-13, and (195)PtNMR measurements revealed that in chloroform solution complex 1 gives a mixture of four different species, which have been unambigously identified as the starting complex 1 in equilbrium with cis-[PtCl(CH3)-(DMSO)(2)] and the two corresponding isomeric aqua-species cis and trans-[PtCl(CH3)(DMSO)(2)](OH2)]. The Pt-195 NMR magnetization transfer technique allowed determination of the rate of interconversion among the various complexes, showing that the direct trans-cis isomerism between the [PtCl(CH3)DMSO)(2)] species is negligible and that the geometrical interconversion occurs through a water-catalyzed pathway. The exchange between free and coordinated DMSO in cis- and trans-[PtCl(CH3)(DMSO)(2)] has been measured by H-1 NMR magnetization transfer experiments. The molecule of DMSO in the position trans to a methyl group was found to be 10-fold more labile than that trans to another sulfur bonded dimethyl sulfoxide. The reactivity of complex 1 in chloroform with a series of monodentate nitrogen ligands having widely different electronic and steric properties has been investigated by H-1 NMR spectorscopy. The utility of this system as precursor for the synthesis of cis and trans-[PtCl(CH3)(DMSO)(am)] is discussed together with the evidence for the factors promoting the prevalence of a geometrical configuration.

  DOI：

  10.1021/ic960428s