[4-(hydroxyl)phenyl]phenylpyren-1-ylphosphine borane | 1187472-64-5

• 英文名称: [4-(hydroxyl)phenyl]phenylpyren-1-ylphosphine borane
• CAS: 1187472-64-5
• 化学式: C₂₈H₂₂BOP
• 分子量: 416.267
• InChiKey: PVCWWQNVGIXRAC-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  [4-(hydroxyl)phenyl]phenylpyren-1-ylphosphine borane 、 (3-iodopropyl)triphenylphosphonium iodide 在 sodium hydride 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 3.0h， 以33%的产率得到[pyrenylphenyl-4-phenoxyphosphineborane]triphenylphosphonium dide
  参考文献：
  名称：

  Synthesis and properties of fluorescence probe for detection of peroxides in mitochondria

  摘要：

  In this study, a new type of fluorescence probe, diphenylpyrenylphosphine- conjugated alkyltriphenyl-phosphonium iodide which was accumulated in mitochondria, has been synthesized. This probe was detected peroxide in living cell. Comparison of the reactivity toward several peroxide indicated that the probe was existed in mitochondrial membrane. Using this probe, generation of peroxide in mitochondria of living cell was successfully visualized. (c) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2010.05.017
• 作为产物：
  描述：

  4-[Phenyl(pyren-1-yl)phosphanyl]phenol 在 硼烷四氢呋喃络合物 作用下， 以 甲苯 为溶剂， 反应 0.25h， 以1.14 g的产率得到[4-(hydroxyl)phenyl]phenylpyren-1-ylphosphine borane
  参考文献：
  名称：

  Synthesis and properties of fluorescence probe for detection of peroxides in mitochondria

  摘要：

  In this study, a new type of fluorescence probe, diphenylpyrenylphosphine- conjugated alkyltriphenyl-phosphonium iodide which was accumulated in mitochondria, has been synthesized. This probe was detected peroxide in living cell. Comparison of the reactivity toward several peroxide indicated that the probe was existed in mitochondrial membrane. Using this probe, generation of peroxide in mitochondria of living cell was successfully visualized. (c) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2010.05.017