| 281206-63-1

• CAS: 281206-63-1
• 化学式: C₁₈H₂₅O₅Rh
• 分子量: 424.299
• InChiKey: PXNYQVIGFZKOIE-GHDUESPLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  异丙烯-2,3-二羟-1,4-双二丙基膦丁烷 、 以 四氢呋喃 为溶剂， 以89.5%的产率得到(4S,5S)-(+)-4,5-bis-(diphenylphosphino-methyl)-2,2-dimethyl-1,3-dioxalane rhodium(I)
  参考文献：
  名称：

  Synthesis and catalytic activity of new supported rhodium(I) complexes for the enantioselective hydrogenation of methyl-(Z)-α-N-acetamidocinnamate

  摘要：

  The polymerizable rhodium complex [(+)-diopRh(AAEMA)] (AAEMA(-): deprotonated form of the ligand 2-(acetoacetoxy)-ethylmethacrylate) was obtained by reaction of (cod)Rh(AAEMA) with (+)-diop at -80 degreesC. Supported chiral complexes have been obtained by copolymerization of [(+)-diopRh(AAEMA)l with NN-dimethylacrylamide and N,N'-methylene-bisacrylamide or by reaction of [(+)-diopRhCl](2) with an opportunely prepared: poly(beta-ketoesterate). Catalytic tests carried out with the homogeneous catalyst or with both its heterogeneous analogues:proved to be active in the enantioselective hydrogenation of methyl-(Z)-alpha-N-acetamidocinnamate yielding (S)-phenylalanine methylester with ee's up to 67%. (C) 2002 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s1381-1169(01)00424-1