1-trimethylsiloxy-3,7,10-trimethylgermatrane | 131498-79-8

• 英文名称: 1-trimethylsiloxy-3,7,10-trimethylgermatrane
• CAS: 131498-79-8
• 化学式: C₁₂H₂₇GeNO₄Si
• 分子量: 350.026
• InChiKey: DDPBADAKVHOYBX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为反应物：
  描述：

  1-trimethylsiloxy-3,7,10-trimethylgermatrane 在 氢氟酸 作用下， 以 异丙醇 为溶剂， 以60%的产率得到1-fluoro-3,7,10-trimethylgermatrane
  参考文献：
  名称：

  A facile synthesis of 1-halo- and 1-organoxygermatranes

  摘要：

  Interaction of the readily available 1-trimethylsiloxygermatranes (1a, 1b) with various halogenating reagents (Me3SiBr, Me3SiI, HF and SOCl2) has given the 1-halogermatranes (2a-2f). The 1-halogermatranes (2a, 2b) have been converted into the corresponding 1-organoxygermatranes by treatment with trialkylalkoxystannanes (3a-3f). The corresponding 1-organoxygermatranes (4d, 4e, 4f) were made by interaction of 1-hydroxygermatrane monohydrate with the corresponding hydroxy derivatives).

  DOI：

  10.1016/0022-328x(91)83089-m

文献信息

• Preparation of germatranyl triflates: reactions of germatranes N(CH2CHRO)3X (X=Br, OTf, OSiMe3; R=H, Me) with lithium reagents
  作者：Sergey S. Karlov、Pavel L. Shutov、Novruz G. Akhmedov、Markus A. Seip、Jörg Lorberth*、Galina S. Zaitseva*

  DOI：10.1016/s0022-328x(99)00739-1

  日期：2000.4

  New germatranes N(CH2CHRO)(3)GeOTf (4a, R = H; 4b, R = Me) were prepared in quantitative yield by treatment of N(CH2CHRO)(3)GeOSiMe3 (2a and 2b), with Me3SiOTf. The reactions of germatranes N(CH2CHRO)(3)GeX [3a, X = Br, R = H; 4a, X = OSO2CF3, R = H; 4b, X = OSO2CF3, R = Me; 2a, X = OSiMe3, R = H; 2b, X = OSiMe3, R = Me] with LiY reagents were studied. A series of germatranes N(CH2CHRO)(3)GeY [5a, R = H, Y = Ind (indenyl); 5b, R = Me, Y = Ind; 6a, R = H, Y = N(SiMe3)(2); 6b, R = Me, Y = N(SiMe3)(2); 7a, R = H, Y = Cp (cyclopentadienyl); 7b, R = Me, Y = Cp; 8a, R = H, Y = Flu (fluorenyl); 9a, R = H, Y = t-Bu] were obtained by nucleophilic substitution with the corresponding LiY reagent. Reactions of N(CH2CHMeO)(3)GeOSiMe3 (2b) and N(CH2CH2O)(3)GeBr (3a) with excess n-BuLi and of N(CH2CH2O)(3)GeOSiMe3 (2a) with excess LiNMe2 led to the formation of n-Bu4Ge and (Me2N)(4)Ge, The structures of new germatranes 4a, 4b, 6b and 7b were confirmed by NMR spectroscopy, mass spectrometry and elemental analyses. (C) 2000 Elsevier Science S.A. All rights reserved.