naringenin/DMβCD complex | 1453473-01-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: naringenin/DMβCD complex
• CAS: 1453473-01-2
• 化学式: C₁₅H₁₂O₅*C₅₆H₉₈O₃₅
• 分子量: 1603.63
• InChiKey: OHQBUSLIPAMFGE-XBHNMOMISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.56
• 重原子数：
  111.0
• 可旋转键数：
  22.0
• 环数：
  24.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  487.04
• 氢给体数：
  10.0
• 氢受体数：
  40.0

反应信息

• 作为产物：
  描述：

  二甲基环糊精 、 (S)-柚皮素 以 乙醇 、 水 为溶剂， 反应 120.0h， 生成 naringenin/DMβCD complex
  参考文献：
  名称：

  Preparation and characterization of inclusion complexes of naringenin with β-cyclodextrin or its derivative

  摘要：

  The inclusion complexation behavior, characterization and binding ability of naringenin with beta-cyclodextrin and its derivatives were investigated in both solution and the solid state by means of XRD, DSC, SEM, H-1 and 2D NMR and UV-vis spectroscopy. The results showed that the water solubility and thermal stability of naringenin were obviously increased in the inclusion complex with cyclodextrins.This satisfactory water solubility and high thermal stability of the naringenin/CD complexes will be potentially useful for their application as herbal medicines or healthcare products. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carbpol.2013.07.010