[H-(N(6)-benzylaminopurine)][Ru(II)Cl3(DMSO)3] | 1072015-00-9

• 英文名称: [H-(N(6)-benzylaminopurine)][Ru(II)Cl3(DMSO)3]
• CAS: 1072015-00-9
• 化学式: C₆H₁₈Cl₃O₃RuS₃*C₁₂H₁₁N₅*H
• 分子量: 668.095
• InChiKey: IPZNOXPBBQRIQT-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  盐酸 、 dichlorotetrakis(dimethylsulfoxide)ruthenium(II) 、 6-苄氨基嘌呤 以 乙醇 为溶剂， 生成 [H-(N(6)-benzylaminopurine)][Ru(II)Cl3(DMSO)3]
  参考文献：
  名称：

  Ruthenium(III) complexes with modified nucleobases: N6-Substituted adenines

  摘要：

  New chlorido-dimethylsulfoxide-ruthenium(III) complexes with different N-6-substituted adenines have been prepared and characterized. Three ruthenium complexes have been structurally characterized by X-ray diffraction crystallography: [(RuCl4)-Cl-III(DMSO)[H-(N-6-pentyladenine)]] (1), [(RuCl4)-Cl-III(DMSO)[H-(N-6-hexyladenine)]] (2) and [(RuCl4)-Cl-III(DMSO)[H-(N-6,N-6-dibutyladenine)]] (3). In all cases ruthenium ion show octahedral geometry coordinated to four chlorido ligands and one S coordinated sulfoxide (DMSO). The coordination sphere is completed by an adenine moiety coordinated to Ru(III) via N(9) and protonated at N(3). Other similar complexes have been obtained with N-6-propyladenine, [(RuCl4)-Cl-III(DMSO)[H-(N-6-propyladenine)]] - 0.5EtOH (4) and N-6-benzylaminopurine (BAP) [(RuCl4)-Cl-III(DMSO)[H-(BAP)]]center dot 0.5H(2)O (5) which have been spectroscopically characterized. Otherwise, in. different reaction conditions, we have obtained an out sphere complex of Ru(II), [H-(BAP)][(RuCl3)-Cl-II(DMSO)(3)] (6), with identical complex unit than the structurally solved [H-(creat)][(RuCl3)-Cl-II(DMSO)(3)] (7) which was included for comparison purposes. Preliminary electrophoretic mobility and atomic force microscopy (AFM) studies of the interaction between Ru(III) compounds and plasmidic DNA pBR322 have been performed. These results show different morphological changes in plasmidic DNA forms. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2008.06.013