4-(4-(2-(2-thienyl)ethoxy)phenyl)-4-oxobutyric acid | 478162-61-7

• 英文名称: 4-(4-(2-(2-thienyl)ethoxy)phenyl)-4-oxobutyric acid
• 英文别名: 4-(4-(2-(thien-2-yl)ethoxy)phenyl)-4-oxobutyric acid；4-Oxo-4-[4-(2-thiophen-2-ylethoxy)phenyl]butanoic acid
• CAS: 478162-61-7
• 化学式: C₁₆H₁₆O₄S
• 分子量: 304.367
• InChiKey: PNDZWGOLDKGBQI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  21
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  91.8
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Compounds for the treatment of metabolic disorders
  申请人：——

  公开号：US20030149107A1

  公开（公告）日：2003-08-07

  Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed.

  适用于治疗各种代谢性疾病的化合物，如胰岛素抵抗综合征、糖尿病、高脂血症、脂肪肝病、虚弱、肥胖、动脉粥样硬化和动脉硬化的化合物已被披露。
• Compound for the treatment of metabolic disorders
  申请人：Sharma Shalini

  公开号：US20050090555A1

  公开（公告）日：2005-04-28

  Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed.

  本发明涉及一种用于治疗各种代谢障碍的化合物，如胰岛素抵抗综合症、糖尿病、高脂血症、脂肪肝病、消瘦、肥胖症、动脉粥样硬化和动脉硬化等。
• COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS
  申请人：Sharma Shalini

  公开号：US20070105958A1

  公开（公告）日：2007-05-10

  Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed.

  本发明揭示了一些化合物，用于治疗各种代谢性疾病，如胰岛素抵抗综合征、糖尿病、高脂血症、脂肪肝病、消瘦、肥胖症、动脉粥样硬化和动脉硬化等。
• CROSSLINKED BIODEGRADABLE RESIN CONTINUOUS FOAMED SHEET AND METHOD FOR PRODUCTION THEREOF
  申请人：TORAY INDUSTRIES, INC.

  公开号：EP1449869A1

  公开（公告）日：2004-08-25

  The foam sheet of the present invention is biodegradable, can be recycled, has good processability, is lightweight, exhibits excellent appearance, has practically satisfactory heat resistance and is more acceptable to the environment. There is provided a crosslinked biodegradable resin continuous foam sheet comprising biodegradable resin, and has an expansion rate of about 1.5 to about 50 and a gel fraction of about 3% or more. There is further provided a method for producing the foam sheet comprising the steps of: (1) preparing a sheet from a resin composition comprising a biodegradable resin, a thermal decomposable blowing agent and a crosslinking promoter; (2) irradiating the resulting sheet with an ionizing radiation to crosslink the resin composition; and (3) subjecting the crosslinked sheet to heat treatment to continuously prepare a crosslinked foam sheet. Thus, the foam sheet of the present invention can be used in a wide range of practical applications such as, for example, interior materials for an automobile, thermal insulators such as a pipe covering, cushioning materials such as a tape core and the like.

  本发明的泡沫板可生物降解、可回收、加工性好、重量轻、外观极佳、耐热性几乎令人满意，对环境更容易接受。 本发明提供了一种交联生物可降解树脂连续泡沫塑料片材，它由生物可降解树脂组成，膨胀率约为 1.5 至 50，凝胶部分约为 3% 或更多。 还提供了一种生产泡沫片材的方法，包括以下步骤(1) 用包含可生物降解树脂、可热分解发泡剂和交联促进剂的树脂组合物制备片材；(2) 用电离辐射照射所得片材，使树脂组合物交联；以及 (3) 将交联片材进行热处理，以连续制备交联泡沫片材。 因此，本发明的泡沫片材可广泛应用于各种实际领域，例如汽车内饰材料、管道覆盖层等隔热材料、胶带芯等缓冲材料等。
• Polyamide composition comprising amorphous polyamide and/or polyester with enhanced and uniform electrical conductivity
  申请人：RHODIA OPERATIONS

  公开号：US10253184B2

  公开（公告）日：2019-04-09

  Provided is a composition comprising a) at least one semi-crystalline polyamide, b) at least one conductive material, and c) at least one amorphous polyamide, and optionally d) at least one polyester. The composition may further comprise e) at least one filler and f) at least one additive.

  所提供的组合物包含 a) 至少一种半结晶聚酰胺，b) 至少一种导电材料，c) 至少一种无定形聚酰胺，以及可选的 d) 至少一种聚酯。该组合物还可进一步包含 e) 至少一种填料和 f) 至少一种添加剂。