| 404849-92-9

• CAS: 404849-92-9
• 化学式: C₂₈H₃₅BrP₂Pd
• 分子量: 619.857
• InChiKey: BLMCTGWSVCRLFP-ARDORAJISA-M

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  、 水 、 silver trifluoromethanesulfonate 、 丙酮 以 水 、 丙酮 为溶剂， 以95%的产率得到
  参考文献：
  名称：

  Development of the First P-Stereogenic PCP Pincer Ligands, Their Metallation by Palladium and Platinum, and Preliminary Catalysis

  摘要：

  The potentially tridentate P-stereogenic [P*CP*] ligands 1,3-{bis[(tert-butyl)(phenyl)phosphino]methyl}-benzene and 1,3-[bis[(tert-butyl)(phenyl) phosphino]methyl]-2-bromobenzene have been synthesized as the protected phosphine-borane adducts. Deprotection with a secondary amine affords the free phosphine ligand which can be metallated by Pd and Pt with standard metal synthons. Two of the resultant [P*CP*] metal complexes have been characterized by X-ray crystallography. The complexes exhibit a C-2-symmetric environment about the remaining binding site of the square-planar center, with t-Bu groups filling two quadrants of the open site. The Pd complexes can be converted by use of a Ag salt to the analogous aquo complex, which is catalytically active in the aldol condensation of methyl 2-isocyanoacetate and benzaldehyde. Preliminary results and comparisons with previously reported catalysts with more distal C-stereogenicity are presented.

  DOI：

  10.1002/1522-2675(20011114)84:11<3519::aid-hlca3519>3.0.co;2-9
• 作为产物：
  描述：

  tris(dibenzylideneacetone)dipalladium(0) chloroform complex 、 1,3-{bis[(tert-butyl)(phenyl)phosphino]methyl}benzene 以 苯 为溶剂， 以19%的产率得到
  参考文献：
  名称：

  Development of the First P-Stereogenic PCP Pincer Ligands, Their Metallation by Palladium and Platinum, and Preliminary Catalysis

  摘要：

  The potentially tridentate P-stereogenic [P*CP*] ligands 1,3-{bis[(tert-butyl)(phenyl)phosphino]methyl}-benzene and 1,3-[bis[(tert-butyl)(phenyl) phosphino]methyl]-2-bromobenzene have been synthesized as the protected phosphine-borane adducts. Deprotection with a secondary amine affords the free phosphine ligand which can be metallated by Pd and Pt with standard metal synthons. Two of the resultant [P*CP*] metal complexes have been characterized by X-ray crystallography. The complexes exhibit a C-2-symmetric environment about the remaining binding site of the square-planar center, with t-Bu groups filling two quadrants of the open site. The Pd complexes can be converted by use of a Ag salt to the analogous aquo complex, which is catalytically active in the aldol condensation of methyl 2-isocyanoacetate and benzaldehyde. Preliminary results and comparisons with previously reported catalysts with more distal C-stereogenicity are presented.

  DOI：

  10.1002/1522-2675(20011114)84:11<3519::aid-hlca3519>3.0.co;2-9