| 934994-26-0

• CAS: 934994-26-0
• 化学式: C₁₈H₂₅FeNO
• 分子量: 327.25
• InChiKey: FSYBTYKUENIHOD-NJHZPMQHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  、 、 碘甲烷 在 n-BuLi 作用下， 以 四氢呋喃 为溶剂， 以75%的产率得到(S)-(E)-1-methoxy-3-methyl-N-(1-ferrocenylethylidenyl)-pentan-2-amine
  参考文献：
  名称：

  New Ortho-Directing Group for Lithiation:  Use of a Methoxy−Imino Auxiliary for the Synthesis of Chiral Ortho-Substituted Acetyl- and Propionylferrocenes

  摘要：

  Ortho lithiation of acetylferrocene and propionylferrocene followed by addition of chlorosilane and diiodoethane was totally enantioselective when a chiral methoxy-imino auxiliary was used as an easily removable ortho-directing group. Enantiopure (R)-o-iodoacetylferrocene and (R)-o-iodopropionylferrocene were obtained. The structure of (R)-o-iodoacetylferrocene was confirmed by X-ray crystallography.

  DOI：

  10.1021/om0609620
• 作为产物：
  描述：

  乙酰基二茂铁 、 L-亮氨醇 以 甲苯 为溶剂， 生成 、
  参考文献：
  名称：

  New Ortho-Directing Group for Lithiation:  Use of a Methoxy−Imino Auxiliary for the Synthesis of Chiral Ortho-Substituted Acetyl- and Propionylferrocenes

  摘要：

  Ortho lithiation of acetylferrocene and propionylferrocene followed by addition of chlorosilane and diiodoethane was totally enantioselective when a chiral methoxy-imino auxiliary was used as an easily removable ortho-directing group. Enantiopure (R)-o-iodoacetylferrocene and (R)-o-iodopropionylferrocene were obtained. The structure of (R)-o-iodoacetylferrocene was confirmed by X-ray crystallography.

  DOI：

  10.1021/om0609620