(4-(N-benzylmethylaminomethyl)-4'-methyl-2,2'-bipyridine)Re(CO)3Cl | 330671-21-1

• 英文名称: (4-(N-benzylmethylaminomethyl)-4'-methyl-2,2'-bipyridine)Re(CO)3Cl
• 英文别名: (bpyN)Re(CO)3Cl
• CAS: 330671-21-1
• 化学式: C₂₃H₂₁ClN₃O₃Re
• 分子量: 609.098
• InChiKey: VRJBNEOYUSQHEL-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  吡啶 、 (4-(N-benzylmethylaminomethyl)-4'-methyl-2,2'-bipyridine)Re(CO)3Cl 、 silver trifluoromethanesulfonate 以 四氢呋喃 、 乙醇 、 二氯甲烷 为溶剂， 以54%的产率得到[(bpyN)Re(CO)3(py)](OTf)
  参考文献：
  名称：

  Rhenium Bipyridine Complexes for the Recognition of Glucose

  摘要：

  Bipyridine ligands containing pendant methyl, amino, and amino-boronic acid groups were synthesized. Coordination complexes of these ligands with rhenium were prepared straightforwardly and in good yield. The fluorescence behavior of the Re complexes was studied as a function of pH and exposure to various concentrations of glucose. The methyl bipyridine complex showed no change in fluorescence with pH, the amino derivative showed a rapid decrease from low pH to neutral, and the amino-boronate derivative showed little change from pH 4 to 10. Fluorescence quenching was observed at high pH as expected on the basis of a photoinduced electron transfer (PET) signaling mechanism. This behavior can be explained on the basis of the first oxidation and reduction potentials of these complexes. Glucose testing showed a significant dependence on the solvent system used. In pure methanol, the rhenium boronate complex exhibited a 55% fluorescence intensity increase upon increasing glucose concentration from 0 to 400 mg/dL. However, in 50 vol % methanollphosphate buffered saline, none of the complexes showed significant response in the glucose range of physiological interest.

  DOI：

  10.1021/ic010202b
• 作为产物：
  描述：

  五羰基氯铼(I) 、 4-(N-benzylmethylaminomethyl)-4'-methyl-2,2'-bipyridine 以 二氯甲烷 、 甲苯 为溶剂， 以96%的产率得到(4-(N-benzylmethylaminomethyl)-4'-methyl-2,2'-bipyridine)Re(CO)3Cl
  参考文献：
  名称：

  Rhenium Bipyridine Complexes for the Recognition of Glucose

  摘要：

  Bipyridine ligands containing pendant methyl, amino, and amino-boronic acid groups were synthesized. Coordination complexes of these ligands with rhenium were prepared straightforwardly and in good yield. The fluorescence behavior of the Re complexes was studied as a function of pH and exposure to various concentrations of glucose. The methyl bipyridine complex showed no change in fluorescence with pH, the amino derivative showed a rapid decrease from low pH to neutral, and the amino-boronate derivative showed little change from pH 4 to 10. Fluorescence quenching was observed at high pH as expected on the basis of a photoinduced electron transfer (PET) signaling mechanism. This behavior can be explained on the basis of the first oxidation and reduction potentials of these complexes. Glucose testing showed a significant dependence on the solvent system used. In pure methanol, the rhenium boronate complex exhibited a 55% fluorescence intensity increase upon increasing glucose concentration from 0 to 400 mg/dL. However, in 50 vol % methanollphosphate buffered saline, none of the complexes showed significant response in the glucose range of physiological interest.

  DOI：

  10.1021/ic010202b