1,1'-bis[(p-methylthiophenylgold(I)diphenyl)phosphino]ferrocene | 185335-12-0

• 英文名称: 1,1'-bis[(p-methylthiophenylgold(I)diphenyl)phosphino]ferrocene
• CAS: 185335-12-0
• 化学式: C₄₈H₄₂Au₂FeP₂S₂
• 分子量: 1194.72
• InChiKey: IATCRGOFRJZLNV-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  (1,1'-双(二苯基膦)二茂铁)二氯化二金 、 4-甲苯硫酚 在 NaOH 作用下， 以 甲醇 、 丙酮 为溶剂， 以59%的产率得到1,1'-bis[(p-methylthiophenylgold(I)diphenyl)phosphino]ferrocene
  参考文献：
  名称：

  New potentially cytotoxic thiolatogold(I) complexes of 1,1′-bis(diphenylphosphino)ferrocene

  摘要：

  1,1'-Bis[chlorogold(I) diphenylphosphino] ferrocene (1) was chosen as the starting material to synthesize new thiolato gold(I) complexes. This has been achieved by substituting the chlorine atoms by monofunctional and bifunctional thiolates affording 'open' thiolatogold complexes and trimetallic ferrocenophane-type structures, respectively. The new 1,1'-bis(2,6-dithia-1-phosphanyl)ferrocene (7) containing directly linked P and S atoms was also prepared but no gold complex was obtained. Compound 2 crystallizes in the monoclinic space group P2(1)/n with a=10.263(2), b=21.064(4), c=16.259(3) Angstrom, beta=97.06(2)degrees and V=3.488(1) Angstrom(3). The distance between the two gold atoms (3.06 A) indicates a significant contact interaction. Compounds 2-5 have allowed antitumoral efficiency on human bladder and colon carcinoma.

  DOI：

  10.1016/s0020-1693(96)05111-0