trans-[RuCl2(PPh3)Ph2P(o,o'-C6H4CH2NHCH2C5H4N)] | 958463-14-4

• 英文名称: trans-[RuCl2(PPh3)Ph2P(o,o'-C6H4CH2NHCH2C5H4N)]
• CAS: 958463-14-4
• 化学式: C₄₃H₃₈Cl₂N₂P₂Ru
• 分子量: 816.712
• InChiKey: VDYXTPOHEYUDCY-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  tris(triphenylphosphine)ruthenium(II) chloride 、 N-(2-(diphenylphosphaneyl)benzyl)-1-(pyridin-2-yl)methanamine 以 二氯甲烷 为溶剂， 以82%的产率得到trans-[RuCl2(PPh3)Ph2P(o,o'-C6H4CH2NHCH2C5H4N)]
  参考文献：
  名称：

  [RuCl₂(PPh₃)(PNN‘)] Complexes as Efficient Catalysts in Transfer Hydrogenation of Ketones

  摘要：

  Ruthenium complexes of the general formula [RuCl2(PPh3)(PNN')] have been obtained from tridentate PNN' ligands containing phosphine (P), amine or imine (N), and pyridyl donor groups (N'). The imino ligand Ph2P(o,o'-C6H4CH=NCH2C5H4N) (a) has been synthesized from Ph2P(2-C6H4CHO) and 2-(aminomethyl)pyridine, whereas amino Ph2P(o,o'-C6H4CH2NHCH2C5H4N) (b) is prepared by the reduction of a with NaBH4. The complexes trans-[RuCl2(PPh3)(PNN')] [PNN' = b, (1); a, (2)] containing a five-membered NN' cycle have been isolated in high yield by the reaction of RuCl2(PPh3)(3) with b and a, respectively. By the same route and using the ligand Ph2P(o,o'-C6H4CH=NCH2CH2C5H4N)] (c), the complex cis-[RuCl2(PPh3)(c)] (3) was isolated, and it displays a different stereochemistry as a result of the different size of the tridentate ligand. For the amino derivative 1, an X-ray diffraction experiment was carried out. Treatment of [RuHCl(PPh3)(3)] with the ligands a or b leads to the monohydride complexes trans-[RuHCl(PPh3)(PNN')] [PNN' = b, (4); a, (5)]. Complexes 1-5 have been proven to catalyze the transfer hydrogenation of linear, cyclic, and aromatic ketones to secondary alcohols in 2-propanol at reflux and in the presence of (CH3)(2)CHONa with a very high rate (TOF values up to 250 000 h(-1)). The trans derivatives 1 and 2 containing the amino and imino functions catalyze the reduction of acetophenone with the same activity (TOF = 190 000 and 185 000 h(-1), respectively), suggesting that the C=N group is reduced during catalysis. A lower activity has been observed for complexes 3-5.

  DOI：

  10.1021/om700647k