dichloro-[2-(2,6-diisopropylphen yl)iminomethylquinoline]platinum(II) | 1432584-54-7

• 英文名称: dichloro-[2-(2,6-diisopropylphen yl)iminomethylquinoline]platinum(II)
• CAS: 1432584-54-7
• 化学式: C₂₂H₂₄Cl₂N₂Pt
• 分子量: 582.432
• InChiKey: CILHXUSSAOMDCT-UWQGMDFESA-L

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  喹啉-2-甲醛 以 甲醇 、 二氯甲烷 、 水 为溶剂， 反应 15.0h， 生成 dichloro-[2-(2,6-diisopropylphen yl)iminomethylquinoline]platinum(II)
  参考文献：
  名称：

  Imino-quinolyl palladium(II) and platinum(II) complexes: Synthesis, characterization, molecular structures and cytotoxic effect

  摘要：

  Imino-quinolyl ligands L1-L5 were synthesized by condensation reaction sand obtained in good yields. Reactions of the ligands with either PdCl2(cod) or K-2[PtCl4] gave the corresponding palladium(II) and platinum(II) complexes 1-10 also in good yields. All the compounds were characterized by elemental analysis, IR, H-1 and C-13 NMR spectroscopy. X-ray crystallography was used to confirm the structures of these compounds. Molecular structures of 3 and 5 showed that the ligands coordinate to the metal center through the two nitrogen atoms, generating a distorted square planar geometry around the palladium atom. The new complexes exhibited remarkable cytotoxic activities against MCF-7 and HT-29 cancer cell lines. (C) 2013 Elsevier B. V. All rights reserved.

  DOI：

  10.1016/j.ica.2013.02.029