[Mo(CF₃SO₃)(η³-C₃H₅)(CO)₂(1,10-phenanthroline)] | 357933-77-8

• 英文名称: [Mo(CF₃SO₃)(η³-C₃H₅)(CO)₂(1,10-phenanthroline)]
• 英文别名: [Mo(CF₃SO₃)(η³-C₃H₅)(CO)₂(phen)]；(1,10-phenanthroline)(η3-allyl)dicarbonylmolybdenum trifluoromethanesulfonate；[Mo(η3-C3H5)(OSO2CF3)(CO)2(phenanthroline)]；[Mo(OTf)(η3-C3H5)(CO)2(phen)]；[Mo(triflate)(CO)2(η3-allyl)(1,10-phenanthroline)]；[Mo(OTf)(CO)2(η3-C3H5)(phen)]
• CAS: 357933-77-8
• 化学式: C₁₈H₁₃F₃MoN₂O₅S
• 分子量: 522.313
• InChiKey: DVZXBQAUCLFABP-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  吡啶 、 [Mo(CF₃SO₃)(η³-C₃H₅)(CO)₂(1,10-phenanthroline)] 反应 2.0h， 生成
  参考文献：
  名称：

  具有可变芳香表面积的 NN 配体的钼 (II) 烯丙基二羰基配合物对粘附和非粘附人类癌细胞的生物活性

  摘要：

  合成了一系列通式为 [Mo(allyl)(CO)2(NN)(py)]+ 的七个钼 (II) 烯丙基二羰基配合物，其中 NN 是具有可变芳族表面积的双齿螯合多吡啶配体采用新的两步法，并通过 IR 和 NMR 光谱、ESI 质谱和元素分析进行​​全面表征。正辛醇/水分配系数 logP 随着 NN 配体的大小从 –0.4 增加到 +1.8。用各种检测方法研究了对粘附 HT-29 和 MCF-7 以及非粘附 NALM-6 人类癌细胞系的生物活性，还可以深入了解细胞死亡的机制。大多数标题化合物在所有三种测试细胞系的低微摩尔浓度范围内都显示出高抗增殖活性，然而，这与确定的 logP 值没有太大关系。细胞凋亡可以被证明是选定化合物和细胞系细胞死亡的主要途径，对于最活跃的复合物，细胞凋亡设置为 5 μM。有趣的是，在通过促凋亡酶 caspase-3 (+) 表达或缺乏 (-) 表达分化的 MCF(+/–)

  DOI：

  10.1002/zaac.201300055
• 作为产物：
  描述：

  [Mo(η3-allyl)Cl(CO)2(1,10-phenanthroline)] 、 silver trifluoromethanesulfonate 以 丙酮 为溶剂， 反应 2.0h， 生成 [Mo(CF₃SO₃)(η³-C₃H₅)(CO)₂(1,10-phenanthroline)]
  参考文献：
  名称：

  具有可变芳香表面积的 NN 配体的钼 (II) 烯丙基二羰基配合物对粘附和非粘附人类癌细胞的生物活性

  摘要：

  合成了一系列通式为 [Mo(allyl)(CO)2(NN)(py)]+ 的七个钼 (II) 烯丙基二羰基配合物，其中 NN 是具有可变芳族表面积的双齿螯合多吡啶配体采用新的两步法，并通过 IR 和 NMR 光谱、ESI 质谱和元素分析进行​​全面表征。正辛醇/水分配系数 logP 随着 NN 配体的大小从 –0.4 增加到 +1.8。用各种检测方法研究了对粘附 HT-29 和 MCF-7 以及非粘附 NALM-6 人类癌细胞系的生物活性，还可以深入了解细胞死亡的机制。大多数标题化合物在所有三种测试细胞系的低微摩尔浓度范围内都显示出高抗增殖活性，然而，这与确定的 logP 值没有太大关系。细胞凋亡可以被证明是选定化合物和细胞系细胞死亡的主要途径，对于最活跃的复合物，细胞凋亡设置为 5 μM。有趣的是，在通过促凋亡酶 caspase-3 (+) 表达或缺乏 (-) 表达分化的 MCF(+/–)

  DOI：

  10.1002/zaac.201300055

文献信息

• Mono‐ and Dimetallic Cyano Complexes with {Mo(η ³ ‐allyl)(CO) ₂ (N−N)} Fragments
  作者：Julio Pérez、Eva Hevia、Lucía Riera、Víctor Riera、Santiago García‐Granda、Esther García‐Rodríguez、Daniel Miguel

  DOI：10.1002/ejic.200390142

  日期：2003.3

  [MoCl(eta(3)-allyl)(CO)(2)(phen)] with NaCN in CH2Cl2/MeOH afforded [Mo(CN)(eta(3)-allyl)(CO)(2)(phen)] [allyl = C3H5 (1a); 2-MeC3H4 (1b)] as the sole products (no products of cyanide attack on the allyl group were detected). Treatment of 1a,b with [Mo(OTf)(eta(3)-C3H5)(CO)(2)(phen)] and NaBAr'(4) in CH2Cl2 yielded the compounds [Mo(eta(3)- allyl)(CO)(2)(phen)}(mu-CN)Mo(eta(3)-C3H5)(CO)(2)(phen)}]BAr'(4)

  在 CH2Cl2/MeOH 中用 NaCN 处理 [MoCl(eta(3)-allyl)(CO)(2)(phen)] 得到 [Mo(CN)(eta(3)-烯丙基)(CO)(2)(phen) )] [烯丙基 = C3H5 (1a); 2-MeC3H4 (1b)] 作为唯一的产物（未检测到氰化物攻击烯丙基的产物）。用 [Mo(OTf)(eta(3)- )(CO)(2)(phen)] 和 NaBAr'(4) 在 中处理 1a,b 产生化合物 [Mo(eta(3)-烯丙基)(CO)(2)(phen)}(mu-CN)Mo(eta(3)- )(CO)(2)(phen)}]BAr'(4) (2a,b)。用 fac-[M(OTf)(CO)(3)(bipy)] (M = Mn, Re) 和 NaBAr'(4) 对 1a 进行类似处理导致 [Mo(eta(3)- )(C
• The Combination of Organometallic {Mo(η³-allyl)(CO)₂(phen)} Fragments and Hard Aquo and Hydroxo Ligands:  Controlled Synthesis and Structural Characterization
  作者：Dolores Morales、M. Elena Navarro Clemente、Julio Pérez、Lucía Riera、Víctor Riera、Daniel Miguel

  DOI：10.1021/om0203882

  日期：2002.11.1

  reaction of [Mo(η3-C3H4-Me-2)Cl(CO)2(phen)] with NaBAr‘4 (Ar‘ = 3,5-bis(trifluoromethyl)phenyl) and H2O allowed the isolation of the aquo complex [Mo(η3-C3H4-Me-2)(OH2)(CO)2(phen)]BAr‘4·2Et2O (1). Deprotonation of 1 afforded a neutral monomeric hydroxo compound isolated as [Mo(η3-C3H4-Me-2)(OH)(CO)2(phen)}2(μ-H2O)] (2), which could be also obtained by reaction of [Mo(η3-C3H4-Me-2)Cl(CO)2(phen)] with

  的[沫（η反应3 -C 3 H ^ 4 -Me-2）氯（CO）2（phen）的]与NaBARhref=https://www.molaid.com/MS_77868 target="_blank">BAr ' 4（AR'= 3,5-双（三氟甲基）苯基）和H 2 ö允许的水合配合物的隔离[沫（η 3 -C 3 H ^ 4 -Me-2）（OH 2）（CO）2（phen）的] BAR” 4 ·2ET 2 O（1）。去质子化1得到分离为[沫（η中性单体羟化合物3 -C 3 H ^ 4 -Me-2）（OH）（CO）2（苯）} 2（μ-H2 O）]（2），其可以通过下述物质反应，也能够得到[沫（η 3 -C 3 H ^ 4 -Me-2）氯（CO）2（phen）的]用KOH在双相CH 2氯2 / H 2 O介质。反应1和2，得到的双核羟-桥连化合物[沫（η 3 -C 3 H ^ 4 -Me-2）（CO）2（苯）} 2（μ-OH）] BAR” 4（图3b）通过羟基配体对水进行亲核取代。
• Reactive Alkoxide Complexes of Groups 6 and 7 Metals
  作者：Eva Hevia、Julio Pérez、Lucía Riera、Víctor Riera、Daniel Miguel

  DOI：10.1021/om010977s

  日期：2002.4.29

  Easily available alkoxo complexes [M(OR)(CO)(3)(bipy)] (M = Mn, Re) and [Mo(OR)(eta(3)-C3H5)(CO)(2)(phen)] react with dimethylacetylenedicarboxylate (DALA-D) to afford the Z-alkenyls resulting from DMAD insertion into the M-OR bonds. Evidence suggesting a nondissociative mechanism is presented.
• Organometallic Complexes with Terminal Imidazolato Ligands and Their Use as Metalloligands
  作者：Eva Gómez、Miguel A. Huertos、Julio Pérez、Lucía Riera、Amador Menéndez-Velázquez

  DOI：10.1021/ic1012395

  日期：2010.10.18

  Compounds [Re(bipy)(CO)(3)(Hlm)]OTf (1) and [Mo(eta(3)-C3H4-R-2)(CO)(2)(Hlm)(Phen)]BAr'(4) [R = Me (2a), H (2b); Ar' = 3,5-bis(trifluoromethyl)phenyl; Hlm = 1H-imidazole] were prepared from 1H-imidazole and either [Re(OTf(bipy)-(CO)(3)] or [MoCl(eta(3)-C3H4-R-2)(CO)(2)(Phen)]. Compounds 1, 2a, and 2b were deprotonated to afford the terminal kappa-N-imidazolate complexes [Re(bipy)(CO)(3)(lm)] (3) and [Mo(eta(3)-C3H4-R-2)(CO)(2)(lm)(phen)] [R = Me (4a), H (4b)], which were fully characterized, including an X-ray structural determination of 3. The topological analysis of the electron density (obtained from the X-ray diffraction study) and its Laplacian were used to characterize the differences in the electron density at the five-membered ring ligand between the imidazole and imidazolate complexes 1 and 3. The reaction of complexes 3, 4a, and 4b with the appropriate organometallic complexes afforded the bimetallic imidazolate-bridged compounds [Re(bipy)(CO)(3)}(2)(mu-lm)]OTf (5), [Mo(eta(3)-C4H7)(CO)(2)(Phen)}(2)(mu-lm)]OTf (6), and [Mo(eta(3)-C3H5)(CO)(2)(phen)}(mu-lm)Re(Phen)(CO)(3)}]OTf (7). The reaction of [Mo(eta(3)-C4H7)(CO)(2)(lm)(Phen)] (4a) with SnClPh3 led to the formation of the trinuclear complex [Mo(eta(3)-C4H7)(CO)(2)(Phen)(mu-lm)}(2)SnPh3}]BAr'(4) (8).
• An Easily Accessed Molybdenum Lewis Acid as a Catalyst for Imine Aziridination
  作者：Dolores Morales、Julio Pérez、Lucía Riera、Víctor Riera、Raúl Corzo-Suárez、Santiago García-Granda、Daniel Miguel

  DOI：10.1021/om010958i

  日期：2002.4.1

  The complex [MoCl(eta(3)-C3H5)(CO)(2)(phen)] was prepared in a one-pot manner from Mo(CO)(6), allyl chloride, and 1,10-phenanthroline (phen). This complex reacted with AgOTf to afford [Mo(OTf)(eta(3)-C3H5)(CO)(2)(phen)] (1). The reaction of 1 with NaBAr'(4) (Ar' = 3,5-bis(trifluoromethyl)phenyl) in CH2Cl2 yielded a solution that catalyzed (1% load of the catalyst) the reaction of ethyl diazoacetate with N-benzylideneaniline to give a mixture of cis(carboxyethyl)-1,3-diphenylaziridine and two enamines. Replacement of phen by chiral ligands based on trans-1,2-diaminocyclohexane failed to induce asymmetry on the obtained aziridine.