iPrNH2·BH3 | 13240-38-5

• 英文名称: iPrNH2·BH3
• 英文别名: isopropylamine borane；NH2(i-Pr)BH3；NH2(iPr)BH3；iPrNH2BH3；(iPr)NH2BH3；H2N(iPr)BH3
• CAS: 13240-38-5
• 化学式: C₃H₁₂BN
• 分子量: 72.946
• InChiKey: WBSSABDUJJLGMJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  iPrNH2·BH3 在 双(三甲基硅烷基)氨基钾 作用下， 以 甲苯 为溶剂， 反应 1.0h， 以72%的产率得到KNH(iPr)BH3
  参考文献：
  名称：

  具有三坐标金属中心的单体氢化锌配合物的便捷合成和晶体结构。

  摘要：

  已经开发了β-二甲叉基氢化锌配合物的便捷合成方法，该配合物结晶为具有三配位锌原子的单体。

  DOI：

  10.1039/b906319f
• 作为产物：
  描述：

  异丙胺 在 dimethyl sulfide borane 作用下， 以 四氢呋喃 为溶剂， 以81%的产率得到iPrNH2·BH3
  参考文献：
  名称：

  Spielmann, Jan; Harder, Sjoerd, Journal of the American Chemical Society, 2009, vol. 131, p. 5064 - 5065

  摘要：

  DOI：

文献信息

• Direct preparation and structure determination of tertiary and secondary amine boranes from primary or secondary amine boranes
  作者：Amal Shibli、Hijazi Abu Ali、Israel Goldberg、Morris Srebnik

  DOI：10.1016/j.jorganchem.2005.01.059

  日期：2005.4

  New secondary and tertiary amine borane derivatives were prepared in a one-pot reaction starting from primary amine boranes. The reaction involves treatment of an amine borane with 2 equivalents of s-BuLi at −78 °C. In general, mixtures of mono and di metallated products were obtained. Alkyl iodides and benzyl chloride reacted with the lithiated amine, but aldehydes and ketones were reduced. Conversion

  一锅反应从伯胺硼烷开始制备新的仲胺和叔胺硼烷衍生物。该反应涉及在-78°C下用2当量的s -BuLi处理胺基硼烷。通常，获得单和双金属化产物的混合物。烷基碘和苄基氯与锂化的胺反应，但醛和酮被还原。如通过NMR确定的，转化率高，但是在色谱分离后获得中至低产率，这可能是由于在二氧化硅上的分解所致。获得了化合物3a，3b和3c的晶体结构。
• Chemoselective Reduction of Phenyl Ketones with Amino Alcohol–Borane Complexes
  作者：Shinichi Itsuno、Takashi Wakasugi、Koichi Ito、Akira Hirao、Seiichi Nakahama

  DOI：10.1246/bcsj.58.1669

  日期：1985.6

  prepared from borane and amino alcohols. The reagent is very effective for chemoselective reduction of ketones in the presence of esters, oxime ethers, tertiary amides, nitriles, halides, and acyl chlorides. The polymeric reagent prepared from borane and polymer-supported amino alcohol was also prepared easily. Aldehydes are highly selectively reduced to primary alcohols in the presence of ketone with the

  以硼烷和氨基醇为原料制备了一种新型还原剂。在酯、肟醚、叔酰胺、腈、卤化物和酰氯存在下，该试剂对酮的化学选择性还原非常有效。由硼烷和聚合物负载的氨基醇制备的聚合试剂也很容易制备。在酮的存在下，醛与聚合物试剂被高度选择性地还原为伯醇。简单的过滤从聚合试剂中干净地分离出未变化的酮，聚合试剂水解后仅得到伯醇作为产物。聚合物试剂通过硼烷处理再生，可以重复使用。
• Studies of aminoboranes. Part II. Pyrolysis of monoalkylamine-boranes: some aminoborane trimers (1,3,5-trialkylcyclotriborazanes) and dimers
  作者：M. P. Brown、R. W. Heseltine、L. H. Sutcliffe

  DOI：10.1039/j19680000612

  日期：——

  Trimeric aminoboranes (RNH·BH2)3, where R = Me, Et, Pr, Bu, and But, each of which occurs in two forms, have been prepared by pyrolyses of the corresponding amine-boranes RNH2,BH3. The dimeric aminoborane (ButNH·BH2)2 was also obtained from pyrolysis of ButNH2,BH3 and a similar dimer (PriNH·BH2)2 was the only aminoborane which could be isolated from the pyrolysis of PriNH2,BH3. Proton magnetic resonance

  通过热解相应的胺-硼烷RNH 2，BH 3，可以制备三聚氨基硼烷（RNH·BH 2）3，其中R = Me，Et，Pr，Bu和Bu t分别以两种形式存在。二聚氨基硼烷（BU吨NH·BH 2）2还从卜的热解获得吨NH 2，BH 3和类似的二聚体（镨我NH·BH 2）2是其中可以从热解分离的唯一氨基硼烷PR我NH 2，BH 3。已经研究了氨基硼烷三聚体的质子磁共振光谱，并且已将异构体指定为顺式和反式构型。
• Synthesis of amine boranes
  申请人：Cartolano Anthony Rocco

  公开号：US20100130780A1

  公开（公告）日：2010-05-27

  A method for preparing an amine borane from an alkali metal borohydride and an amine salt. The alkali metal borohydride is allowed to react with 0.95 to 1.05 equivalents of the amine salt in a solvent which contains water and an amine.

  从碱金属硼氢化物和胺盐制备胺硼烷的方法。将碱金属硼氢化物与相当于0.95至1.05当量的胺盐在含有水和胺的溶剂中反应。
• Studies of aminoboranes. Part I. Reactions involving transfer of hydrogen from N-monoalkyl-substituted aminoboranes and amine–boranes to dimethylaminoborane
  作者：M. P. Brown、R. W. Heseltine、D. W. Johnson

  DOI：10.1039/j19670000597

  日期：——

  Dimethylaminoborane reacts with trimeric aminoboranes (RNH·BH2)3(R = Et and Pr) to give corresponding borazines: Me2N·BH2+⅓(RNH·BH2)3→ Me2NH,BH3+⅓(RNBH)3 Dimethylaminoborane also reacts with amine–boranes, RNH2,BH3(R = Me, Prn, and Pri). From reactions involving propyl- and isopropyl-amine–borane, stable 1,1-dimethyl-3,5-dialkylcyclotriborazanes, which are in effect cyclic mixed adducts, Me2N·BH2,2RNH·BH2

  二甲基氨基硼烷与三聚氨基硼烷（RNH·BH 2）3（R = Et和Pr）反应生成相应的硼嗪：Me 2 N·BH 2 +⅓（RNH·BH 2）3 → Me 2 NH，BH 3 +⅓（RNBH ）3二甲基氨基硼烷也与胺-硼烷RNH 2，BH 3（R = Me，Pr n和Pr i）反应。从涉及丙基和异丙基胺硼烷，稳定1,1-二甲基-3,5- dialkylcyclotriborazanes，其在效果环状混合加合物的反应中，Me 2 N·BH 2，2RNH·BH 2，已获得。