[Cu(8-quinolinecarboxaldehyde thiosemicarbazone)(SO4)]2 | 1293919-17-1

• 英文名称: [Cu(8-quinolinecarboxaldehyde thiosemicarbazone)(SO4)]2
• CAS: 1293919-17-1
• 化学式: C₂₂H₂₀Cu₂N₈O₈S₄
• 分子量: 779.806
• InChiKey: KPWNBKJAQVGXJF-SOBWDFFCSA-J

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  copper(ll) sulfate pentahydrate 、 8-quinoline aldehyde thiosemicarbazone 以 硫酸 为溶剂， 生成 [Cu(8-quinolinecarboxaldehyde thiosemicarbazone)(SO4)]2
  参考文献：
  名称：

  Synthesis and structure of copper(II) coordination compounds with 8-quinolinecarboxaldehyde thio- and 4-phenylthiosemicarbazones

  摘要：

  8-Quinolinecarboxaldehyde thiosemicarbazone (HL) and copper form compounds with a metal : ligand ratio of 1 : 1 in which the ligand is either the neutral molecule or the monohydric acid anion. Its acidic properties are enhanced not only as a result of coordination but also due to the electronic effect of substituents in the thiosemicarbazide moiety. 8-Quinolinecarboxaldehyde 4-phenylthiosemicarbazone (HL1) is coordinated only as the anion. The structures of [Cu(HL)SO4](2), [Cu(L)NO3](2), and [Cu(L-1)NO3](2) center dot 0.25H(2)O, and free HL1 were studied. The tendency of the complexes to dimerization and association with acid anions or sulfur atoms of the organic ligands as bridges was established. In binuclear compounds with closely spaced magnetic centers, no exchange interaction between them was found. The copper coordination compounds with HL are able to suppress the growth of cancer cells 41M and SK-BR-3 and are promising objects for investigation as anticancer drugs.

  DOI：

  10.1134/s0036023610090093