10-(4-(bis(pyridin-2-ylmethyl)amino)phenyl)-5,5-difluoro-1,3,7,9-tetramethyl-5H-5l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium | 1221790-61-9

• 英文名称: 10-(4-(bis(pyridin-2-ylmethyl)amino)phenyl)-5,5-difluoro-1,3,7,9-tetramethyl-5H-5l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium
• CAS: 1221790-61-9
• 化学式: C₃₁H₃₀BF₂N₅
• 分子量: 521.421
• InChiKey: JHVWYRFFPXIOBK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  4-(1,4-dioxa-7,13-dithia-10-azacyclopentadecan-10-yl)benzaldehyde 、 10-(4-(bis(pyridin-2-ylmethyl)amino)phenyl)-5,5-difluoro-1,3,7,9-tetramethyl-5H-5l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium 在 哌啶 、 溶剂黄146 作用下， 以 苯 为溶剂， 反应 1.0h， 以20%的产率得到
  参考文献：
  名称：

  Selective Manipulation of ICT and PET Processes in Styryl-Bodipy Derivatives: Applications in Molecular Logic and Fluorescence Sensing of Metal Ions

  摘要：

  Remarkably versatile chemistry of Bodipy dyes allows the design and straightforward synthesis of multivalent-multitopic derivatives, which, with judicious selection of metal ion ligand pairs based on known affinities, affords control and manipulation of photoinduced electron transfer and internal charge transfer processes as desired. We have demonstrated that metal ions acting as modulators (or inputs, in digital design parlance) can generate absorbance changes in accordance with the operation of a half-adder. In addition, an AND logic gate in the emission mode was delivered using a different binucleating arrangement of ligands. A molecular equivalent of a three-input AND logic gate was also obtained exploiting differential binding affinities of metal ions for different ligands. The results suggest that different metal ions can be used as nonannihilating inputs, selectively targeting various ligands incorporated within a single fluorophore, and with careful design, diverse photophysical processes can be selectively modulated, resulting in a range of signals, useful in molecular logic design, and offering an enticing potential for multianalyte chemosensors.

  DOI：

  10.1021/ja1008163
• 作为产物：
  描述：

  4-(bis(pyridin-2-ylmethyl)amino)benzaldehyde 在 三氟化硼乙醚 、 三乙胺 、 三氟乙酸 作用下， 以 二氯甲烷 为溶剂， 反应 25.0h， 生成 10-(4-(bis(pyridin-2-ylmethyl)amino)phenyl)-5,5-difluoro-1,3,7,9-tetramethyl-5H-5l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium
  参考文献：
  名称：

  从虚拟到物理：化学逻辑门的集成。

  摘要：

  部件集成：在分子水平上进行高级信息处理需要集成逻辑门，迄今为止，这仅在虚拟上是可行的。现在，通过“点击”化学将两个独立工作的AND分子逻辑门组合在一起，从而形成集成逻辑门，这些逻辑门的响应恰好是这种集成方案所预测的。

  DOI：

  10.1002/anie.201104228

文献信息

• Functionalized Fe3O4 Nanoparticles for Detecting Zinc Ions in Living Cells and Their Cytotoxicity
  作者：Gyusik Kang、Hyunjong Son、Jung Mi Lim、Hee-Seek Kweon、In Su Lee、Dongmin Kang、Jong Hwa Jung

  DOI：10.1002/chem.201200294

  日期：2012.5.7

  The zinc tank: A new fluoro‐chromogenic chemosensor based on BODIPY‐functionalized Fe3O4 nanoparticles (1) has been prepared. Chemoprobe 1 exhibits high selectivity for Zn2+ over other competing metal ions tested. Moreover, confocal microscopy experiments established that 1 can be used for detecting Zn2+ levels in living cells (see figure).

  锌罐：基于BODIPY功能化的Fe 3 O 4纳米颗粒（1）的新型荧光显色化学传感器已经制备。化学探针1对Zn 2+的选择性比其他竞争性金属离子高。此外，共聚焦显微镜实验确定1可用于检测活细胞中的Zn 2+水平（见图）。